phostensin Antibody (C-1): sc-365398
- phostensin Antibody (C-1) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 121-420 mapping within an internal region of phostensin of human origin
- recommended for detection of phostensin of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for phostensin Antibody (C-1). This work is in progress.
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Phostensin Antibody (C-1) is a mouse monoclonal IgG2b antibody that detects phostensin in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Phostensin, also known as KIAA1949, is a 613 amino acid protein that plays a crucial role in cellular regulation by acting as a regulatory subunit that targets protein phosphatase 1 (PP1) to F-Actin within the cytoskeleton. Anti-phostensin antibody (C-1) targeting is vital for the proper functioning of the cytoskeleton, which is essential for maintaining cell shape, enabling cellular movement, and facilitating intracellular transport. The interaction between phostensin and PP1 is particularly important in the context of cellular processes such as division and apoptosis, as PP1 helps modulate the phosphorylation state of various substrates, thereby influencing a wide range of signaling pathways. Phostensin is predominantly expressed in tissues such as the spleen, ovary, lung, and liver, and exists in two isoforms due to alternative splicing events, which may contribute to functional diversity and regulatory capabilities within different cellular contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
phostensin Antibody (C-1) | sc-365398 | 200 µg/ml | $322.00 |