P-cadherin Antibody (D-6): sc-514481

P-cadherin Antibody (D-6) is a mouse monoclonal IgG2a kappa light chain antibody that detects P-cadherin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-P-cadherin antibody (D-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. P-cadherin, a member of the cadherin family, plays a crucial role in cell-cell adhesion, which is essential for maintaining tissue integrity and facilitating morphogenetic processes. P-cadherin is primarily located in the plasma membrane, where P-cadherin forms adherens junctions that connect adjacent cells, thereby contributing to the structural stability of tissues. P-cadherin′s presence is particularly important in epithelial tissues, where P-cadherin helps regulate cellular interactions and signaling pathways that influence cell proliferation and differentiation. Additionally, P-cadherin′s interaction with cytoplasmic proteins, such as β-catenin, is vital for the modulation of cadherin-mediated adhesion and signaling, underscoring P-cadherin′s significance in both normal physiological processes and pathological conditions, including cancer metastasis.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-P-cadherin Antibody (D-6) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-P-cadherin Antibody (D-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

P-cadherin Antibody (D-6) Specifications

Alternate Product Name: CDH3

Product Clone Name: D-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 607-630

Epitope Target: P-cadherin

Epitope Species: human

Product Reactivity/Detection: P-cadherin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for P-cadherin Antibody (D-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred P-cadherin antibody is P-cadherin Antibody (A-10): sc-74545.