Lomeguatrib CAS: 192441-08-0
MF: C10H8BrN5OS
MW: 326.17
A monosaccharide-linked inhibitor of MGMT.

Lomeguatrib (CAS 192441-08-0)

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Nombres Alternativos: PaTrin-2
Solicitud: Lomeguatrib is a monosaccharide-linked inhibitor of MGMT
Número de CAS: 192441-08-0
Peso Molecular: 326.17
Fórmula Molecular: C10H8BrN5OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Lomequartrib is an inhibitor of O6 methylguanin-DNA methyltransferase (MGMT) with an IC50 value of 0.009 µM in cell-free extracts from HeLa S3 cells.

Estado de Materia :
Solid
Solubilidad :
Soluble in DMSO (100 mM).
ALMACENAMIENTO :
Store at 4° C
Punto de Fusión :
227.23° C (Predicted)
Punto de ebullición :
683.75° C at 760 mmHg (Predicted)
Densidad :
1.87 g/cm3 (Predicted)
Indice de Refracción :
n20D 1.80 (Predicted)
IC50 :
6-O-methylguanine-DNA methyltransferase: IC50 = 3 nM (human)
Valores de pK :
pKa: 9.42 (Predicted), pKb: 3.09 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3025944
Número MDL :
MFCD09837804
SMILES :
C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N

Descargar SDS (MSDS)

CERTIFICADO DE ANÁLISIS

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