KIF9 Antibody (4E9): sc-517075
- KIF9 Antibody (4E9) is a mouse monoclonal IgG2a κ KIF9 antibody, cited in 1 publications, provided at 100 µg/ml
- raised against amino acids 691-789 representing partial length KIF9 of human origin
- recommended for detection of KIF9 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for KIF9 Antibody (4E9). This work is in progress.
KIF9 Antibody (4E9) is a mouse monoclonal IgG2a kappa light chain antibody that detects KIF9 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-KIF9 antibody (4E9) is available as the non-conjugated format. KIF9, a member of the kinesin family, is a vital cytoskeletal motor protein that plays a significant role in intracellular transport and cell division. This 790 amino acid protein is characterized by its kinesin-motor domain and exists in two isoforms, with expression levels that are developmentally regulated across various tissues, including the brain, kidney, spleen, lung, and testis. KIF9 maintains the connection between the microtubule organizing center (MTOC) and the nucleus during interphase, which is crucial for proper cell division and organization. KIF9 interacts with the protein Gem, potentially linking to the cytoskeleton and facilitating its role in transporting organelles and vesicles within the cell. Additionally, KIF9 may function as a plus-ended microtubule motor, possibly existing as a homodimer, which underscores its importance in cellular dynamics and the maintenance of cellular architecture.
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KIF9 Antibody (4E9) References:
- All kinesin superfamily protein, KIF, genes in mouse and human. | Miki, H., et al. 2001. Proc Natl Acad Sci U S A. 98: 7004-11. PMID: 11416179
- The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9. | Piddini, E., et al. 2001. EMBO J. 20: 4076-87. PMID: 11483511
- Kinesin superfamily proteins (KIFs) in the mouse transcriptome. | Miki, H., et al. 2003. Genome Res. 13: 1455-65. PMID: 12819144
- NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins. | Takano, K., et al. 2007. Nucleic Acids Res. 35: 2513-21. PMID: 17403691
- Microtubule-nucleus interactions in Dictyostelium discoideum mediated by central motor kinesins. | Tikhonenko, I., et al. 2009. Eukaryot Cell. 8: 723-31. PMID: 19286984
- Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. | Nakagawa, T., et al. 1997. Proc Natl Acad Sci U S A. 94: 9654-9. PMID: 9275178
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KIF9 Antibody (4E9) | sc-517075 | 100 µg/ml | $322.00 |