Integrin β3/ITGB3/CD61 Antibody (SAP): sc-13579

Integrin β3 Antibody (SAP) is a mouse monoclonal IgG1 antibody that detects Integrin β3 in mouse, rat, and human samples through applications such as western blotting (WB), immunofluorescence (IF), and flow cytometry (FCM). Integrin β3 is a crucial component of integrin receptors, which are heterodimers formed by the noncovalent association of α and β subunits. Specifically, Integrin β3 pairs with various α subunits to form receptors that mediate cell adhesion to the extracellular matrix and facilitate communication between cells. The importance of Integrin β3 lies in its role in binding to ligands such as fibronectin and vitronectin, which are essential for cell signaling and structural integrity. Additionally, Integrin β3 is involved in the regulation of cell migration, proliferation, and survival, making Integrin β3 a key player in processes such as wound healing and immune responses. The ability of Integrin β3 to interact with specific proteins, including the αv subunit, enhances functionality in mediating cellular responses to the extracellular environment. Anti-Integrin β3 antibody (SAP) is an invaluable tool for researchers studying the dynamics of cell adhesion and signaling pathways in various biological contexts.

The preferred Integrin αV/β3/CD51/CD61 antibody is Integrin αV/β3/CD51/CD61 Antibody (23C6): sc-7312.