Integrin β3/ITGB3/CD61 Antibody (MHF4): sc-53351

Integrin β3 Antibody (MHF4) is a mouse monoclonal IgG1 antibody that detects Integrin β3 in mouse, rat, and human samples through immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin β3 is a crucial component of integrin receptors, which are heterodimers formed by the noncovalent association of alpha and beta subunits. Specifically, anti-Integrin β3 antibody (MHF4) pairs with various alpha subunits to form receptors that mediate cell adhesion to the extracellular matrix, playing a vital role in processes such as wound healing, immune response, and tissue repair. Integrin β3 is predominantly located on the cell surface, where Integrin β3 interacts with ligands like fibronectin and vitronectin, facilitating cell signaling and communication. This interaction is essential for the activation of integrin-mediated responses, which include cell migration and proliferation. Furthermore, Integrin β3 is involved in the regulation of platelet aggregation, making Integrin β3 a significant target for therapeutic interventions in cardiovascular diseases. Integrin β3 monoclonal antibody (MHF4) enables researchers to gain insights into the functional dynamics of Integrin β3 and its role in various biological processes, enhancing our understanding of cellular behavior in health and disease.

The preferred Integrin αV/β3/CD51/CD61 antibody is Integrin αV/β3/CD51/CD61 Antibody (23C6): sc-7312.