Integrin β2/ITGB2/CD18 Antibody (M18/2.a.12.7): sc-81727

Integrin β2 Antibody (M18/2.a.12.7) is a rat monoclonal IgG2a antibody that detects Integrin β2 in mouse samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow cytometry (FCM). Integrin β2 monoclonal antibody (M18/2.a.12.7) is raised by immunizing rats with cytotoxic T cell glycoproteins of mouse origin. Integrin β2 (M18/2.a.12.7) antibody recognizes a crucial component of the integrin family, which consists of heterodimers formed by noncovalently associated transmembrane α and β subunits. Specifically, anti-Integrin β2 antibody (M18/2.a.12.7) pairs with different α subunits to form receptors that play a vital role in cell adhesion and signaling. Integrin β2 is primarily located on the cell surface, where interactions with extracellular matrix components and other cells facilitate processes such as leukocyte migration and immune response. This localization is essential for proper immune system functioning, allowing adhesion of immune cells to sites of inflammation and injury, promoting effective immune surveillance and response. Integrin β2 monoclonal antibody (M18/2.a.12.7) recognizes a protein that participates in signaling pathways regulating cell growth, differentiation, and apoptosis, underscoring importance in maintaining cellular homeostasis and responding to environmental cues. Integrin β2 interacts with key proteins such as intercellular adhesion molecules (ICAMs), fibronectin, and collagen, facilitating leukocyte adhesion, migration, and immune signaling. With diverse applications and critical role in cellular processes, anti-Integrin β2 antibody (M18/2.a.12.7) serves as an invaluable tool for researchers studying integrin-mediated functions in mouse models.

The preferred Integrin β2/ITGB2/CD18 antibody is Integrin β2/ITGB2/CD18 Antibody (CTB104): sc-8420.