HLA-C Antibody (H-5): sc-166134

HLA-C Antibody (H-5) is a mouse monoclonal IgG3 kappa light chain antibody that detects HLA-C of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). HLA-C Antibody (H-5) is available in a non-conjugated form, providing flexibility for various experimental needs. HLA-C, a member of the major histocompatibility complex (MHC) class I molecules, plays a crucial role in immune response by presenting peptides derived from intracellular proteins to CD8+ cytotoxic T cells, thereby facilitating recognition and elimination of infected or malignant cells. HLA-C consists of a heavy chain non-covalently associated with β-2-microglobulin, forming a stable complex essential for antigen presentation. The polymorphic nature of HLA-C allows for diverse peptide binding, vital for immune system recognition of various pathogens. Expression of HLA-C is regulated by cytokines, which influence immune responses and disease susceptibility. Understanding HLA-C structural dynamics provides insights into T cell receptor interactions and implications in transplant rejection and autoimmune disorders.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HLA-C Antibody (H-5) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-HLA-C Antibody (H-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HLA-C Antibody (H-5) Specifications

Alternate Product Name: HLAC

Product Clone Name: H-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 91-123

Epitope Target: HLA-C

Epitope Species: human

Product Reactivity/Detection: HLA-C

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for HLA-C Antibody (H-5): P: Blocking Peptide

The preferred HLA-C antibody is HLA-C Antibody (C-8): sc-166088.