CD44 Antibody (SFF-2): sc-65405
- CD44 Antibody (SFF-2) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against HCAM of human origin
- recommended for detection of HCAM of human origin by IF, IHC(P) and FCM
- See CD44 (DF1485): sc-7297 for CD44 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD44 Antibody (SFF-2). This work is in progress.
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SEE ALSO...
HCAM Antibody (SFF-2) is a mouse monoclonal IgG antibody that detects HCAM in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). HCAM, also known as CD44, is a 742 amino acid single-pass type I membrane protein that plays a crucial role in cell adhesion and migration, which are vital processes in embryogenesis, immune response, and tumor metastasis. HCAM functions primarily as a receptor for hyaluronic acid (HA) and interacts with various ligands, including osteopontin (OPN), facilitating both cell-cell and cell-matrix interactions. HCAM′s structure features a Link domain, which is essential for binding to HA, and undergoes alternative splicing, resulting in multiple isoforms such as CD44R, CDw44, CD44S, CD44H, and CD44E. The CD44H isoform shows high expression in cancer tissues, indicating potential involvement in tumor progression and making HCAM a critical target for cancer research. Anti-HCAM antibody (SFF-2) serves as an invaluable tool for studying cell adhesion and migration dynamics in various biological contexts, particularly in oncology research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD44 Antibody (SFF-2) | sc-65405 | 100 µg/ml | $322.00 |