Glipizide (CAS 29094-61-9)
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Glipizide is a compound investigated in the field of biochemistry, particularly for its interaction with the sulfonylurea receptor 1 (SUR1) on pancreatic beta cells. Its action in stimulating insulin release from these cells is a focal point of research, providing insights into the regulation of insulin secretion. Additionally, studies involving glipizide include the examination of its effects on ATP-sensitive potassium channels, as it provides a model for understanding channel modulation and the downstream effects on cellular membrane potential. The compound is also used in research related to the mechanisms of glucose homeostasis and insulin sensitivity. Furthermore, glipizide is a subject in the study of chemical delivery systems, where researchers explore various formulation strategies to optimize its bioavailability and stability.
Glipizide (CAS 29094-61-9) References
- Glipizide suppresses embryonic vasculogenesis and angiogenesis through targeting natriuretic peptide receptor A. | Gu, Q., et al. 2015. Exp Cell Res. 333: 261-272. PMID: 25823921
- Glipizide blocks renal interstitial fibrosis by inhibiting AKT signaling pathway. | Yang, G., et al. 2017. Eur Rev Med Pharmacol Sci. 21: 867-872. PMID: 28272693
- Glipizide sensitizes lung cancer cells to TRAIL-induced apoptosis via Akt/mTOR/autophagy pathways. | Nazim, UM., et al. 2017. Oncotarget. 8: 100021-100033. PMID: 29245957
- Polymorphs and Amorphous State of Glipizide: Preparation and Solid-State Transformations. | Xu, K., et al. 2021. J Pharm Sci. 110: 1718-1726. PMID: 33160976
- The Physico-Chemical Properties of Glipizide: New Findings. | Bruni, G., et al. 2021. Molecules. 26: PMID: 34073973
- Glipizide Combined with ANP Suppresses Breast Cancer Growth and Metastasis by Inhibiting Angiogenesis through VEGF/VEGFR2 Signaling. | Mao, G., et al. 2022. Anticancer Agents Med Chem. 22: 1735-1741. PMID: 34515012
- Total Synthesis of Glipizide and Glibenclamide in Continuous Flow. | Sagandira, CR., et al. 2021. Chemistry. 27: 16028-16035. PMID: 34633700
- The effects of glipizide on DNA damage and nuclear transport in differentiated 3T3-L1 adipocytes. | Cevik, M., et al. 2022. Mol Biol Rep. 49: 1151-1159. PMID: 35013863
- Glipizide ameliorates human poly(Q) mediated neurotoxicity by upregulating insulin signalling in Drosophila disease models. | Tandon, S. and Sarkar, S. 2023. Biochem Biophys Res Commun. 645: 88-96. PMID: 36680941
- Glipizide Alleviates Periodontitis Pathogenicity via Inhibition of Angiogenesis, Osteoclastogenesis and M1/M2 Macrophage Ratio in Periodontal Tissue. | Guo, X., et al. 2023. Inflammation.. PMID: 37289398
- Glipizide: a review of its pharmacological properties and therapeutic use. | Brogden, RN., et al. 1979. Drugs. 18: 329-53. PMID: 389600
- Glyburide and glipizide, second-generation oral sulfonylurea hypoglycemic agents. | Prendergast, BD. 1984. Clin Pharm. 3: 473-85. PMID: 6435940
- NIDDM in the cat: treatment with the oral hypoglycemic medication, glipizide. | Ford, SL. 1995. Vet Clin North Am Small Anim Pract. 25: 599-615. PMID: 7660535
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glipizide, 1 g | sc-204768 | 1 g | $150.00 | |||
Glipizide, 5 g | sc-204768A | 5 g | $612.00 |