γ2 Tubulin Anticuerpo (SP-30): sc-134228

4.0(1)

Escriba un comentario Haga una pregunta

Ficha técnica

- γ2 Tubulin Anticuerpo (SP-30) es un monoclonal de ratón IgG_2a κ, ver las 1 publicaciones, proporcionado como 100 µg/ml
- raised against recombinant γ2 Tubulin protein of human origin
- recomendado para detectarγ2 Tubulin de mouse, rat y human origen, mediante WB, IP, IF y ELISA
- Contacte con nosotros para recibir GRATIS 10 µg de muestra de γ2 Tubulin (SP-30): sc-134228.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for γ2 Tubulin Antibody (SP-30). This work is in progress.

VER TAMBIÉN ....

Más Tubulin Anticuerpos incluyendo α 1 Tubulin, α 3 Tubulin, α 4 Tubulin, α Tubulin, β Tubulin, β 2 Tubulin, β 3 Tubulin, δ Tubulin, ε Tubulin y γ Tubulin
ChemCruz™ Químicos Tubulin para análisis funcionales de las repuestas celulares a Tubulin

γ2 Tubulin Antibody (SP-30) - Western Blotting - Image 64795

γ2 Tubulin Antibody (SP-30) - Immunofluorescence - Image 64794

Haga click en la imagen para agrandarla

γ2 Tubulin Antibody (SP-30) is an IgG2a κ mouse monoclonal γ2 Tubulin antibody (also designated γ2 Tubulin antibody or gamma Tubulin antibody) suitable for the detection of γ2 Tubulin of mouse, rat and human origin by WB, IP, IF and ELISA. γ2 Tubulin Antibody (SP-30) is available as the non-conjugated anti-γ2 Tubulin antibody form. Tubulin exists as five distinct forms, designated α, β, γ, δ and e, all of which function as critical components of the cytoskeleton, specifically forming heterodimers which multimerize to produce microtubule filaments. γ2 Tubulin, also known as TUBG2, is a 451 amino acid member of the Tubulin family and, like other Tubulin proteins, plays a role in the minus-end nucleation of microtubule assembly. The gene encoding γ2 Tubulin maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

References:

Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton. | Herreros, L., et al. 2000. J Biol Chem. 275: 26436-40. PMID: 10840040
The gamma-tubulin gene family in humans. | Wise, DO., et al. 2000. Genomics. 67: 164-70. PMID: 10903841
Gene knockout analysis of two gamma-tubulin isoforms in mice. | Yuba-Kubo, A., et al. 2005. Dev Biol. 282: 361-73. PMID: 15893303
Analysis of the gamma-tubulin sequences: implications for the functional properties of gamma-tubulin. | Burns, RG. 1995. J Cell Sci. 108 (Pt 6): 2123-30. PMID: 7673333
Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin. | Tassin, AM., et al. 1998. J Cell Biol. 141: 689-701. PMID: 9566969

Especies	Nombre del Gen	Gen ID	Ubicación en el cromosoma	Numero de Acceso de Isoforma (ARNm)	Número de Acceso de la Proteína	Número OMIM™
Human	TUBG2	Entrez Gene ID: 27175	17q21.2	XM_011524614, XM_017024453, XM_017024454, XM_017024455, XM_017024456, XM_017024457, NM_001320509, NM_016437	UniProt ID: Q9NRH3	605785

Descargar Ficha Técnica

Descargar Protocolo

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-γ2 Tubulin Antibody (SP-30) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-γ2 Tubulin Antibody (SP-30) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

I am using γ2 Tubulin (SP-30): sc-134228 for immunofluorescence, what dilution of this antibody should I use?

Preguntado por: AbPolly

Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining

Respondida por: Technical Support

Fecha de publicación: 2017-03-24

Rated 4 de 5 por TS de Good mono for WB and IF with HeLa samples Good mono for WB and IF with HeLa samples.

Fecha de publicación: 2013-05-23

Elija una tienda

Elija un idioma

Elija una Divisa

γ2 Tubulin Anticuerpo (SP-30): sc-134228

ENLACES RÁPIDOS

VER TAMBIÉN ....

References:

I am using γ2 Tubulin (SP-30): sc-134228 for immunofluorescence, what dilution of this antibody should I use?

γ2 Tubulin Anticuerpo (SP-30): sc-134228

ENLACES RÁPIDOS

VER TAMBIÉN ....

References:

I am using &gamma;2 Tubulin (SP-30): sc-134228 for immunofluorescence, what dilution of this antibody should I use?

I am using γ2 Tubulin (SP-30): sc-134228 for immunofluorescence, what dilution of this antibody should I use?