FluoroGold™ (CAS 223769-64-0)
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FluoroGold™ is a highly effective neuronal retrograde tracer compatible with any histological processing technique and can be further combined with a second marker such as autoradiography, HRP histochemistry, immunocytochemistry, a second fluorescent tracer, fluorescent counterstain, etc. FluoroGold™ can be used on virtually any central or peripheral nervous system structure for analysis of retrograde transport. In the peripheral nervous system, ganglia and peripheral targets can be studied. For studies of peripheral nerve, the nerve should be cut or damaged and either dipped in, or injected with a 5% solution of FluoroGold™. The survival time for FluoroGold™ should be varied and is dependent on the specific neuronal system under study. For retrograde transport, the survival times should be varied from 4 days to 14 days. In addition, since FluoroGold™ remains fast within retrogradely labeled neurons, survival times of several months will also produce excellent results. For iontophoresis, a 2-5 day survival time is recommended. It is estimated that transport occurs at about 2 cm per day for mammals, and is slower for cold-blooded animals.
FluoroGold™ (CAS 223769-64-0) References
- Anatomy of olivocochlear neurons in the hamster studied with FluoroGold. | Sánchez-González, MA., et al. 2003. Hear Res. 185: 65-76. PMID: 14599694
- Zincergic innervation of medial prefrontal cortex by basolateral projection neurons. | Cunningham, MG., et al. 2007. Neuroreport. 18: 531-5. PMID: 17413652
- Dendrites of medial olivocochlear neurons in mouse. | Brown, MC. and Levine, JL. 2008. Neuroscience. 154: 147-59. PMID: 18313859
- Projections of olfactory bulbs to the olfactory and vomeronasal cortices. | Pro-Sistiaga, P., et al. 2008. Neuroreport. 19: 1541-4. PMID: 18797313
- Activation of serotonergic neurons during salicylate-induced tinnitus. | Caperton, KK. and Thompson, AM. 2011. Otol Neurotol. 32: 301-7. PMID: 21192277
- Fluoro-Gold: a new fluorescent retrograde axonal tracer with numerous unique properties. | Schmued, LC. and Fallon, JH. 1986. Brain Res. 377: 147-54. PMID: 2425899
- Calibration and standardisation of graded optic nerve injuries in rats. | Huang, HB., et al. 2015. Neurol Res. 37: 638-49. PMID: 25816832
- The brainstem efferent acoustic chiasm in pigmented and albino rats. | Reuss, S., et al. 2016. Hear Res. 332: 1-6. PMID: 26657095
- Enhancing Fluorogold-based neural tract tracing. | Mondello, SE., et al. 2016. J Neurosci Methods. 270: 85-91. PMID: 27288218
- Afferent and efferent projections of the anterior cortical amygdaloid nucleus in the mouse. | Cádiz-Moretti, B., et al. 2017. J Comp Neurol. 525: 2929-2954. PMID: 28543083
- The iontophoretic application of Fluoro-Gold for the study of afferents to deep brain nuclei. | Pieribone, VA. and Aston-Jones, G. 1988. Brain Res. 475: 259-71. PMID: 3214735
- Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene. | Tabata, K., et al. 2021. Int J Mol Sci. 22: PMID: 34201658
- The parabrachio-subfornical organ projection in the rat. | Gu, GB. and Ju, G. 1995. Brain Res Bull. 38: 41-7. PMID: 7552374
- Fluoro-gold and pentamidine inhibit the in vitro and in vivo release of dopamine in the striatum of rat. | Bowyer, JF., et al. 1993. J Pharmacol Exp Ther. 266: 1066-74. PMID: 8355181
- Organization of inputs to the dorsomedial nucleus of the hypothalamus: a reexamination with Fluorogold and PHAL in the rat. | Thompson, RH. and Swanson, LW. 1998. Brain Res Brain Res Rev. 27: 89-118. PMID: 9622601
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FluoroGold™, 20 mg | sc-358883 | 20 mg | $458.00 | |||
FluoroGold™, 50 mg | sc-358883A | 50 mg | $819.00 |