DDX33 Antibody (F-5): sc-390436
- DDX33 Antibody (F-5) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 621-655 near the C-terminus of DDX33 of human origin
- recommended for detection of DDX33 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG2b BP-HRP is the preferred secondary detection reagent for DDX33 Antibody (F-5) for WB applications. This reagent is now offered in a bundle with DDX33 Antibody (F-5) (see ordering information below).
DDX33 Antibody (F-5) is a mouse monoclonal IgG2b antibody that detects DDX33 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDX33, also known as DHX33, is a 707 amino acid nucleolar protein that plays a crucial role in RNA metabolism, particularly in the assembly of ribonucleoprotein complexes essential for ribosome and spliceosome function. DDX33 is characterized by helicase ATP-binding domain and helicase C-terminal domain, which are vital for unwinding RNA structures, thereby facilitating proper processing and translation of RNA. DDX33′s importance extends to involvement in various cellular processes, including embryogenesis and cellular growth, making DDX33 a significant player in developmental biology and disease states. DDX33 is encoded by a gene located on human chromosome 17, which is a genomic region that harbors over 1,200 genes and is implicated in numerous genetic disorders. Additionally, two isoforms of DDX33 arise from alternative splicing, contributing to functional diversity in different cellular contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DDX33 Antibody (F-5) | sc-390436 | 200 µg/ml | $322.00 | |||
DDX33 Antibody (F-5): m-IgG2b BP-HRP Bundle | sc-548622 | 200 µg Ab; 10 µg BP | $361.00 | |||
DDX33 (F-5) Neutralizing Peptide | sc-390436 P | 100 µg/0.5 ml | $69.00 |