D-myo-Inositol-1,2,3,5-tetraphosphate, sodium salt MF: C6H12O18P4•4Na
MW: 588.00
A soluble second messenger in the transmission of cellular signals.

D-myo-Inositol-1,2,3,5-tetraphosphate, sodium salt

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Nombres Alternativos: 1,2,3,5-IP4 (sodium salt); Ins(1,2,3,5)-P4 (sodium salt)
Solicitud: D-myo-Inositol-1,2,3,5-tetraphosphate, sodium salt is a soluble second messenger in the transmission of cellular signals
Pureza: >98%
Peso Molecular: 588.00
Fórmula Molecular: C6H12O18P44Na
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
* En el Certificado de Análisis específico de lote, puede encontrar información específica (como el contenido en agua).

D-myo-Inositol-1,2,3,5-tetraphosphate, sodium salt is one of the many inositol phosphate isomers that could act as small, soluble second messengers in the transmission of cellular signals. Ins(1,2,3,5)P4 exhibits relatively weak agonist activity at the Ins(1,4,5)P3 receptor expressed in CHO cells, where it induces Ca2+ mobilization with an ED50 value of 93.3 µM, making it nearly less effective than Ins(1,4,5)P3 in the same assay.


References

1 Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361 315-325 (1993). 2 Majerus, P.W. Inositol phosphate biochemistry. Annu Rev Biochem 61 225-250 (1992). 3 Shears, S.B. The versatility of inositol phosphates as cellular signals. Biochim Biophys Acta 1436 49-67 (1998). 4 Burford, N.T., Nahorski, S.R., Chung, S., et al. Binding and activity of the nine possible regioisomers of myo-inositol tetrakisphosphate at the inositol 1,4,5-trisphosphate receptor. Cell Calcium 21 301-310 (1997).

Apariencia :
Lyophilized powder
Estado de Materia :
Solid
ALMACENAMIENTO :
Store at -20° C
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
PubChem CID :
53394604
SMILES :
O[[email protected]@H]1[[email protected]@H](OP([O-])(O)=O)[[email protected]](O)[[email protected]@H](OP([O-])(O)=O)[[email protected]@H](OP([O-])(O)=O)[[email protected]]1OP([O-])(O)=O.[Na+].[Na+].[Na+].[Na+]

Descargar SDS (MSDS)

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