Chloramphenicol-13C6

Chloramphenicol-13C6 is a labeled variant of chloramphenicol, where six carbon atoms are substituted with carbon-13 (13C), a stable isotope that does not alter the chemical or biological properties of the compound but distinctly changes its physical properties in a way that is highly valuable for research purposes. This isotopic enrichment allows for precise and differentiated analysis of chloramphenicol using techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The incorporation of carbon-13 enhances the detection sensitivity and specificity of chloramphenicol in complex sample matrices, making it an excellent tool for tracking the distribution and metabolism of chloramphenicol in environmental and experimental systems. Researchers utilize Chloramphenicol-13C6 primarily in environmental chemistry to investigate how chloramphenicol, as an environmental contaminant, behaves under various conditions, including its degradation products and their impact on ecosystems. This is crucial in studies focused on the persistence of chemical residues in the environment and their potential effects on microbial communities, particularly regarding resistance development. Additionally, Chloramphenicol-13C6 serves as a robust internal standard in quantitative analyses, ensuring accurate quantification and helping to standardize results across different experimental setups, which is essential for developing effective monitoring and mitigation strategies for antibiotic contamination.