CEACAM16 Antibody (A-4): sc-514335
- CEACAM16 Antibody (A-4) is a mouse monoclonal IgG1 κ CEACAM16 antibody provided at 200 µg/ml
- raised against amino acids 317-380 mapping near the C-terminus of CEACAM16 of human origin
- CEACAM16 Antibody (A-4) is recommended for detection of CEACAM16 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CEACAM16 Antibody (A-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for CEACAM16 Antibody (A-4) for WB applications. This reagent is now offered in a bundle with CEACAM16 Antibody (A-4) (see ordering information below).
CEACAM16 Antibody (A-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects CEACAM16 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CEACAM16 antibody (A-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CEACAM16, also known as carcinoembryonic antigen-like 2, is a 484 amino acid single-pass transmembrane protein characterized by two immunoglobulin-like C2-type domains, which play a crucial role in mediating cell adhesion and signaling processes. These domains facilitate interactions with other proteins, influencing cellular communication and immune responses. Such interactions are particularly important in tumor biology, where CEACAM16 may contribute to the regulation of tumor progression and metastasis. Understanding CEACAM16′s structural features and functional implications helps researchers explore potential applications as a biomarker for cancer and other diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CEACAM16 Antibody (A-4) References:
- The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. | Hammarström, S. 1999. Semin Cancer Biol. 9: 67-81. PMID: 10202129
- Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. | Zebhauser, R., et al. 2005. Genomics. 86: 566-80. PMID: 16139472
- Characterization of murine carcinoembryonic antigen gene family members. | Rudert, F., et al. 1992. Mamm Genome. 3: 262-73. PMID: 1638085
- The CEACAM1 transmembrane domain, but not the cytoplasmic domain, directs internalization of human pathogens via membrane microdomains. | Muenzner, P., et al. 2008. Cell Microbiol. 10: 1074-92. PMID: 18081725
- CEACAM1 expression in pancreatic endocrine tumors. | Serra, S., et al. 2009. Appl Immunohistochem Mol Morphol. 17: 286-93. PMID: 19349857
- Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. | Thompson, JA., et al. 1991. J Clin Lab Anal. 5: 344-66. PMID: 1941355
- CEACAM1: a novel urinary marker for bladder cancer detection. | Tilki, D., et al. 2010. Eur Urol. 57: 648-54. PMID: 19487071
- The carcinoembryonic antigen gene family: structure, expression and evolution. | Thompson, J. and Zimmermann, W. 1988. Tumour Biol. 9: 63-83. PMID: 3041547
- Molecular cloning and expression of carcinoembryonic antigen gene family members. | Thompson, JA. 1995. Tumour Biol. 16: 10-6. PMID: 7863217
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CEACAM16 Antibody (A-4) | sc-514335 | 200 µg/ml | $322.00 | |||
CEACAM16 Antibody (A-4): m-IgG Fc BP-HRP Bundle | sc-526357 | 200 µg Ab; 10 µg BP | $361.00 | |||
CEACAM16 Antibody (A-4) AC | sc-514335 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CEACAM16 Antibody (A-4) HRP | sc-514335 HRP | 200 µg/ml | $322.00 | |||
CEACAM16 Antibody (A-4) FITC | sc-514335 FITC | 200 µg/ml | $336.00 | |||
CEACAM16 Antibody (A-4) PE | sc-514335 PE | 200 µg/ml | $349.00 | |||
CEACAM16 Antibody (A-4) Alexa Fluor® 488 | sc-514335 AF488 | 200 µg/ml | $364.00 | |||
CEACAM16 Antibody (A-4) Alexa Fluor® 546 | sc-514335 AF546 | 200 µg/ml | $364.00 | |||
CEACAM16 Antibody (A-4) Alexa Fluor® 594 | sc-514335 AF594 | 200 µg/ml | $364.00 | |||
CEACAM16 Antibody (A-4) Alexa Fluor® 647 | sc-514335 AF647 | 200 µg/ml | $364.00 | |||
CEACAM16 Antibody (A-4) Alexa Fluor® 680 | sc-514335 AF680 | 200 µg/ml | $364.00 | |||
CEACAM16 Antibody (A-4) Alexa Fluor® 790 | sc-514335 AF790 | 200 µg/ml | $364.00 |