Cdc25B Anticuerpo (DCS-162) es un monoclonal de ratón IgG1 κ, ver las 1 publicaciones, proporcionado como 200 µg/ml
producido contra la proteína completa Cdc25B de origen human
Cdc25B Anticuerpo (DCS-162) es recomendado para detectar Cdc25B de human origen, mediante IP, IF, IHC(P) y ELISA
Cdc25B Anticuerpo (DCS-162) es disponible conjugado a agarosa para IP; HRP para WB, IHC(P) y ELISA; y tanto a phycoerythrin como a FITC para IF, IHC(P) y FCM
también disponible conjugado a Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 o Alexa Fluor® 647 para WB (RGB), IF, IHC (P) y FCM
también disponible conjugado a Alexa Fluor® 680 o Alexa Fluor® 790 para WB (NIR), IF y FCM
Contacte con nosotros para recibir GRATIS 10 µg de muestra de Cdc25B (DCS-162): sc-56266.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Cdc25B Antibody (DCS-162) for IHC(P) applications. These reagents are now offered in bundles with Cdc25B Antibody (DCS-162) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
The Cdc2/cyclin B enzyme, involved in regulation of mitosis in eukaryotic cells, is subject to multiple levels of control. Among these, the regulation of the catalytic subunit by Tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B complex, while Tyrosine dephosphorylation, which occurs at the onset of mitosis, directly activates the pre-MPH complex. The Cdc25 gene serves as a rate-limiting mitotic activator, apparently due to its action as the Cdc2 Tyrosine phosphatase. In the absence of Cdc25, Cdc2 accumulates in a Tyrosine phosphorylated state. In addition, Cdc25 proteins from a variety of species have been shown to share a low degree of sequence similarity with other Tyrosine phosphatases. The Cdc25 gene family consists of at least three members that share approximately 40% identity in their most conserved carboxy-terminal sequences.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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