CD4 Antibody (YNB46.1.8): sc-59041

CD4 Antibody (YNB46.1.8) is a rat monoclonal IgG1 antibody specifically developed to detect the human CD4 protein, also known as T4 or Leu-3. Anti-CD4 antibody (YNB46.1.8) recognizes an epitope on the extracellular domain of CD4, a membrane-bound glycoprotein prominently expressed on the surface of T helper cells, macrophages, dendritic cells, and other immune cells. The strategic location of CD4 on the cell membrane is crucial for its role as a co-receptor in T cell receptor (TCR) signaling, where CD4 facilitates binding to class II major histocompatibility complex (MHC) molecules presented by antigen-presenting cells. This interaction enhances the stability and affinity of the TCR-MHC complex, thereby promoting effective T cell activation and initiating robust adaptive immune responses. Additionally, CD4 serves as the primary receptor for HIV, making CD4 an important target for studies on viral entry and immune system interactions. CD4 monoclonal antibody (YNB46.1.8) is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM), ensuring versatile applications in various research settings. Anti-CD4 antibody (YNB46.1.8) reactivity with human CD4 allows researchers to explore expression patterns, functional roles, and regulatory mechanisms of CD4 in immune regulation, T cell development, and disease processes. CD4 (YNB46.1.8) antibody enables scientists to gain valuable insights into the critical functions of CD4, advancing our understanding of immune system dynamics and contributing to the development of targeted therapies and diagnostic tools.

The preferred CD4 antibody is CD4 Antibody (GK1.5): sc-13573.