CD4 Antibody (H129.19): sc-19642
- CD4 Antibody (H129.19) is a rat monoclonal IgG2a, cited in 4 publications, provided at 200 µg/ml
- raised against A.TH. mouse CTL clone A15.1.17
- recommended for detection of CD4 of mouse origin by IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to APC for IF, IHC(P) and FCM
- also provided azide-free for blocking T helper cell responses to antigen or mitogen stimulation, sc-19642 L, 200 µg/0.1 ml
- See CD4 (MT310): sc-19641 for CD4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD4 Antibody (H129.19). This work is in progress.
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CD4 Antibody (H129.19) is a rat monoclonal IgG2a antibody engineered to recognize CD4, also known as T4 or Leu 3, specifically in mouse samples. Anti-CD4 antibody (H129.19) is raised against the A.TH. mouse CTL clone A15.1.17 epitope and is recommended for use in immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM) applications, ensuring precise detection of CD4 in various experimental contexts. CD4 is a membrane-bound glycoprotein composed of four extracellular immunoglobulin-like domains, which are crucial for its function as a co-receptor in T cell activation by enhancing the interaction between the T cell receptor (TCR) and class II major histocompatibility complex (MHC) molecules on antigen-presenting cells. Post-translational modifications, such as glycosylation, play a vital role in maintaining CD4′s stability, proper cell surface localization, and its interactions with other proteins, thereby influencing the effectiveness of the immune response. Additionally, CD4 serves as a primary receptor for the human immunodeficiency virus (HIV), making CD4 a significant target for studies on viral entry and immune system regulation. The strategic localization of CD4 on T helper cells, cortical cells, mature medullary thymocytes, microglial cells, and dendritic cells highlights CD4′s importance in both adaptive and innate immunity. CD4 monoclonal antibody (H129.19) enables accurate identification and characterization of CD4-positive cells, supporting essential research in immunology, including investigations into autoimmune diseases, infectious diseases, and the development of immunotherapies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD4 Antibody (H129.19) | sc-19642 | 200 µg/ml | $322.00 | |||
CD4 Antibody (H129.19) APC | sc-19642 APC | 100 tests in 2 ml | $358.00 | |||
CD4 Antibody (H129.19) APCC7 | sc-19642 APCC7 | 100 tests in 2 ml | $376.00 | |||
CD4 Antibody (H129.19) FITC | sc-19642 FITC | 200 µg/ml | $336.00 | |||
CD4 Antibody (H129.19) L | sc-19642 L | 200 µg/0.1 ml | $322.00 | |||
CD4 Antibody (H129.19) PE | sc-19642 PE | 200 µg/ml | $349.00 |