BID Antibody (E-7): sc-514622
- BID Antibody (E-7) is a mouse monoclonal IgG2a κ, cited in 8 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 172-195 at the C-terminus of BID of human origin
- Anti-BID Antibody (E-7) is recommended for detection of BID of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-BID Antibody (E-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for BID Antibody (E-7) for WB applications. These reagents are now offered in bundles with BID Antibody (E-7) (see ordering information below).
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BID Antibody (E-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects BID in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-BID antibody (E-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BID plays a crucial role in the regulation of apoptosis, acting as a pro-apoptotic member of the Bcl-2 family. BID contains a BH3 domain that enables interaction with anti-apoptotic proteins like Bcl-2 and Bcl-x, effectively countering their death-repressing effects. This interaction is vital for the apoptotic signaling pathway, as BID helps to promote cell death in response to various stress signals, thereby maintaining cellular homeostasis and preventing uncontrolled cell proliferation. BID is predominantly localized in the cytosol but can also be found in membrane fractions, with high expression levels in the kidney and detectable levels in the brain, spleen, liver, testis, and lung. BID′s ability to heterodimerize with other proteins, such as Bax, further underscores BID′s importance in the intricate balance of cell survival and death, making BID (E-7) monoclonal antibody an essential tool for researchers studying apoptosis and related cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BID Antibody (E-7) | sc-514622 | 200 µg/ml | $322.00 | |||
BID Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-526383 | 200 µg Ab; 10 µg BP | $361.00 | |||
BID Antibody (E-7): m-IgG2a BP-HRP Bundle | sc-546614 | 200 µg Ab; 10 µg BP | $361.00 | |||
BID Antibody (E-7) AC | sc-514622 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BID Antibody (E-7) HRP | sc-514622 HRP | 200 µg/ml | $322.00 | |||
BID Antibody (E-7) FITC | sc-514622 FITC | 200 µg/ml | $336.00 | |||
BID Antibody (E-7) PE | sc-514622 PE | 200 µg/ml | $349.00 | |||
BID Antibody (E-7) Alexa Fluor® 488 | sc-514622 AF488 | 200 µg/ml | $364.00 | |||
BID Antibody (E-7) Alexa Fluor® 546 | sc-514622 AF546 | 200 µg/ml | $364.00 | |||
BID Antibody (E-7) Alexa Fluor® 594 | sc-514622 AF594 | 200 µg/ml | $364.00 | |||
BID Antibody (E-7) Alexa Fluor® 647 | sc-514622 AF647 | 200 µg/ml | $364.00 | |||
BID Antibody (E-7) Alexa Fluor® 680 | sc-514622 AF680 | 200 µg/ml | $364.00 | |||
BID Antibody (E-7) Alexa Fluor® 790 | sc-514622 AF790 | 200 µg/ml | $364.00 | |||
BID (E-7) Neutralizing Peptide | sc-514622 P | 100 µg/0.5 ml | $69.00 |