Ageladine A, TFA (CAS 643020-13-7)
Nombres Alternativos:
(4-(4,5-Dibromo-1H-pyrrol-2-yl)-1H-imidazo[4,5-c]-pyridin-2-amine), TFA
Solicitud:
Ageladine A, TFA is a multipurpose inhibitor and pH-sensitive fluorescent dye
Número de CAS:
643020-13-7
Peso Molecular:
471.00
Fórmula Molecular:
C10H7Br2N5•C2HF3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Ageladine A, TFA is a pH-sensitive fluorescent dye which can be used for live imaging in acidic organelles, cells, and whole animals due to its non-toxic nature, however there is limited detection in alkaline solutions. Ageladine A, TFA is trapped in cells and organelles via hydrophobic interactions on the inner side of membranes. It exhibits long-term stability due to limited metabolization, which causes slow photobleaching. Ageladine A, TFA is an angiogenesis inhibitor, and also inhibits the matrix metalloproteinases MMP-1, -2, -8, -9, -12, -13 and the kinases Tyk2, Dyrk2, Dyrk1A, and Rsk-1.
Estado de Materia
:
Solid
Solubilidad
:
Soluble in DMSO, and methanol.
ALMACENAMIENTO
:
Store at 4° C
Indice de Refracción
:
n20D ~1.83 (Predicted)
Fluorescente
:
λex 370 nm, λem 415 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID
:
SMILES
:
C1=CN=C(C2=C1NC(=N2)N)C3=CC(=C(N3)Br)Br
Descargar SDS (MSDS)
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