VEZF1 Antibody (B-4): sc-365560
- VEZF1 Antibody (B-4) is a mouse monoclonal IgG2a κ VEZF1 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 351-516 mapping at the C-terminus of VEZF1 of human origin
- VEZF1 Antibody (B-4) is recommended for detection of VEZF1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-VEZF1 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-365560 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for VEZF1 Antibody (B-4) for WB applications. This reagent is now offered in a bundle with VEZF1 Antibody (B-4) (see ordering information below).
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VEZF1 Antibody (B-4) is a mouse monoclonal IgG2a kappa light chain antibody that detects VEZF1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-VEZF1 antibody (B-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. VEZF1, also known as vascular endothelial zinc finger 1, ZNF161, or DB1, is a crucial nuclear-localizing zinc-finger protein that plays a significant role in the regulation of gene expression within the vascular endothelium. VEZF1 is primarily expressed in the kidneys and skeletal muscle, where VEZF1 functions as an endothelial transcription factor that regulates the expression of the endothelin-1 (ET-1) promoter. VEZF1′s importance lies in its ability to interact with the CT/GC-rich region of the ET-1 promoter, which is essential for the proper assembly of the cardiovascular system during early development. Through activation of various genes involved in vascular development, VEZF1 contributes to the formation and maintenance of the cardiovascular system, highlighting VEZF1′s critical role in both developmental biology and potential implications in vascular-related diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
VEZF1 Antibody (B-4) References:
- Vezf1/DB1 is an endothelial cell-specific transcription factor that regulates expression of the endothelin-1 promoter. | Aitsebaomo, J., et al. 2001. J Biol Chem. 276: 39197-205. PMID: 11504723
- Human zinc finger protein 161, a novel transcriptional activator of the dopamine transporter. | Lee, KH., et al. 2004. Biochem Biophys Res Commun. 313: 969-76. PMID: 14706637
- p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation. | Aitsebaomo, J., et al. 2004. J Biol Chem. 279: 17963-72. PMID: 14966113
- Vascular endothelial zinc finger 1 is involved in the regulation of angiogenesis: possible contribution of stathmin/OP18 as a downstream target gene. | Miyashita, H., et al. 2004. Arterioscler Thromb Vasc Biol. 24: 878-84. PMID: 15031128
- Dosage-dependent requirement for mouse Vezf1 in vascular system development. | Kuhnert, F., et al. 2005. Dev Biol. 283: 140-56. PMID: 15882861
- Metallothionein 1 is a downstream target of vascular endothelial zinc finger 1 (VEZF1) in endothelial cells and participates in the regulation of angiogenesis. | Miyashita, H. and Sato, Y. 2005. Endothelium. 12: 163-70. PMID: 16162438
- Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter. | Koyano-Nakagawa, N., et al. 1994. Mol Cell Biol. 14: 5099-107. PMID: 8035792
- Functional interaction between RhoB and the transcription factor DB1. | Lebowitz, PF. and Prendergast, GC. 1998. Cell Adhes Commun. 6: 277-87. PMID: 9865462
- Vezf1: A Zn finger transcription factor restricted to endothelial cells and their precursors. | Xiong, JW., et al. 1999. Dev Biol. 206: 123-41. PMID: 9986727
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VEZF1 Antibody (B-4) | sc-365560 | 200 µg/ml | $322.00 | |||
VEZF1 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-525891 | 200 µg Ab; 10 µg BP | $361.00 | |||
VEZF1 Antibody (B-4) X | sc-365560 X | 200 µg/0.1 ml | $322.00 | |||
VEZF1 Antibody (B-4) AC | sc-365560 AC | 500 µg/ml, 25% agarose | $424.00 | |||
VEZF1 Antibody (B-4) HRP | sc-365560 HRP | 200 µg/ml | $322.00 | |||
VEZF1 Antibody (B-4) FITC | sc-365560 FITC | 200 µg/ml | $336.00 | |||
VEZF1 Antibody (B-4) PE | sc-365560 PE | 200 µg/ml | $349.00 | |||
VEZF1 Antibody (B-4) Alexa Fluor® 488 | sc-365560 AF488 | 200 µg/ml | $364.00 | |||
VEZF1 Antibody (B-4) Alexa Fluor® 546 | sc-365560 AF546 | 200 µg/ml | $364.00 | |||
VEZF1 Antibody (B-4) Alexa Fluor® 594 | sc-365560 AF594 | 200 µg/ml | $364.00 | |||
VEZF1 Antibody (B-4) Alexa Fluor® 647 | sc-365560 AF647 | 200 µg/ml | $364.00 | |||
VEZF1 Antibody (B-4) Alexa Fluor® 680 | sc-365560 AF680 | 200 µg/ml | $364.00 | |||
VEZF1 Antibody (B-4) Alexa Fluor® 790 | sc-365560 AF790 | 200 µg/ml | $364.00 |