Troponin T-C Antibody (1.BB.157): sc-73237
- Troponin T-C Antibody (1.BB.157) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against full length cardiac troponin T of human origin
- recommended for detection of cardiac muscle troponin T of human and bovine origin by WB and IP
- See Troponin T-C (CT3): sc-20025 for Troponin T-C antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Troponin T-C Antibody (1.BB.157). This work is in progress.
QUICK LINKS
SEE ALSO...
Troponin T-C Antibody (1.BB.157) is a mouse monoclonal IgG1 antibody that detects Troponin T in human and bovine samples through applications such as western blotting (WB) and immunoprecipitation (IP). Anti-Troponin T antibody (1.BB.157) recognizes a critical component of the troponin complex, which plays a vital role in muscle contraction by linking the troponin complex to actin filaments in the muscle thin filament. Troponin T is essential for the regulation of cardiac and skeletal muscle contraction, as Troponin T (1.BB.157) facilitates the conformational changes necessary for muscle fibers to contract in response to calcium ion levels. The structure of Troponin T contains a unique C-terminal domain that interacts with tropomyosin, stabilizing the troponin-tropomyosin complex and ensuring proper muscle function. Mutations or alterations in Troponin T can lead to various cardiac and skeletal muscle disorders, making Troponin T monoclonal antibody (1.BB.157) a significant tool for research in understanding muscle physiology and pathophysiology. Anti-Troponin T antibody (1.BB.157) provides valuable insights into the molecular mechanisms underlying muscle contraction and regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Troponin T-C Antibody (1.BB.157) References:
- Cardiac troponin T in the diagnosis of myocardial injury. | Mair, J., et al. 1992. Crit Rev Clin Lab Sci. 29: 31-57. PMID: 1388708
- Cardiac troponin T release after prolonged strenuous exercise. | Michielsen, EC., et al. 2008. Sports Med. 38: 425-35. PMID: 18416595
- Elevated cardiac troponin T levels in critically ill patients with sepsis. | Vasile, VC., et al. 2013. Am J Med. 126: 1114-21. PMID: 24083646
- Cardiac troponin T degradation in serum is catalysed by human thrombin. | Streng, AS., et al. 2016. Biochem Biophys Res Commun. 481: 165-168. PMID: 27816455
- Basic residues within the cardiac troponin T C terminus are required for full inhibition of muscle contraction and limit activation by calcium. | Johnson, D., et al. 2019. J Biol Chem. 294: 19535-19545. PMID: 31712308
- Clinical Impact of High-Sensitivity Cardiac Troponin T Implementation in the Community. | Ola, O., et al. 2021. J Am Coll Cardiol. 77: 3160-3170. PMID: 34167641
- Exercise Training Increases Serum Cardiac Troponin T Independent of Left Ventricular Mass. | Kong, Z., et al. 2022. Int J Sports Med. 43: 505-511. PMID: 34872117
- Exercise-induced cardiac troponin T release in veteran athletes recovered from COVID-19. | Janssen, SLJE., et al. 2022. Eur J Prev Cardiol. 29: e279-e282. PMID: 35199156
- Aberrant Expression of Cardiac Troponin-T in Lung Cancer Tissues in Association With Pathological Severity. | Tsuruda, T., et al. 2022. Front Cardiovasc Med. 9: 833649. PMID: 35479276
- Fragmentation of human cardiac troponin T after acute myocardial infarction. | Katrukha, IA., et al. 2023. Clin Chim Acta. 542: 117281. PMID: 36918061
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Troponin T-C Antibody (1.BB.157) | sc-73237 | 100 µg/ml | $322.00 |