TBL1 Antibody (H-11): sc-137083
- TBL1 Antibody (H-11) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 211-577 of TBL1X of human origin
- recommended for detection of TBL1X of mouse, rat and human origin and TBL1Y of human origin by WB, IP, IF, IHC(P) and ELISA
- TransCruz reagent for ChIP application (sc-137083 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TBL1 Antibody (H-11) for WB and IHC(P) applications. These reagents are now offered in bundles with TBL1 Antibody (H-11) (see ordering information below).
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TBL1 Antibody (H-11) is a mouse monoclonal IgG1 antibody that detects TBL1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). TBL1, or transducin β-like 1, plays a pivotal role in the regulation of gene expression by functioning as a co-regulator in the nuclear receptor signaling pathway. TBL1 is essential for the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units, thereby influencing the transcriptional activity of various genes. TBL1 is characterized by six β-transducin repeats, which are critical for protein-protein interactions, and exists in two forms: TBL1X, located on the X chromosome, and TBL1Y, found on the Y chromosome. The interaction of TBL1X with histones H2B, H3a, and H4 highlights TBL1′s importance in chromatin remodeling and transcriptional regulation. Notably, defects in TBL1X have been linked to ocular albinism with late-onset sensorineural deafness, underscoring TBL1′s significance in human health. TBL1 (H-11) antibody serves as an invaluable tool for researchers studying the intricate mechanisms of gene regulation and TBL1′s implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TBL1 Antibody (H-11) | sc-137083 | 200 µg/ml | $322.00 | |||
TBL1 Antibody (H-11): m-IgG Fc BP-HRP Bundle | sc-539931 | 200 µg Ab; 10 µg BP | $361.00 | |||
TBL1 Antibody (H-11): m-IgG1 BP-HRP Bundle | sc-541794 | 200 µg Ab; 20 µg BP | $361.00 | |||
TBL1 Antibody (H-11) X | sc-137083 X | 200 µg/0.1 ml | $322.00 |