RBMS2 Antibody (B-4): sc-514918

RBMS2 Antibody (B-4) is a mouse monoclonal IgM antibody that detects RBMS2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RBMS2 antibody (B-4) is available as a non-conjugated monoclonal isotype antibody. RBMS2, also known as RNA-binding motif, single-stranded-interacting protein 2, is a crucial component in regulating various cellular processes, including DNA replication, gene transcription, and apoptosis. RBMS2 consists of 407 amino acids and features two RNA recognition motif (RRM) domains, which are essential for binding single-stranded nucleic acids. Nuclear localization of RBMS2 enables interaction with nuclear RNA and DNA, influencing gene expression and cell cycle progression. RBMS2 has been shown to suppress Cdc2 kinase and Cdc13 cyclin mutant activity, highlighting a role in cell cycle regulation. RBMS2 gene is conserved across several species, including chimpanzees, dogs, cows, mice, rats, and zebrafish, and is mapped to human chromosome 12q13.3, underscoring evolutionary importance and potential as a target for further research in cellular and molecular biology.

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RBMS2 Antibody (B-4) References:

1. Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes.  |  Skerka, C., et al. 1992. J Immunol. 148: 3313-8. PMID: 1533657
2. Large-scale proteomics analysis of the human kinome.  |  Oppermann, FS., et al. 2009. Mol Cell Proteomics. 8: 1751-64. PMID: 19369195
3. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.  |  Mayya, V., et al. 2009. Sci Signal. 2: ra46. PMID: 19690332
4. RBMS2 inhibits the proliferation by stabilizing P21 mRNA in breast cancer.  |  Sun, X., et al. 2018. J Exp Clin Cancer Res. 37: 298. PMID: 30514345
5. RBMS2 Chemosensitizes Breast Cancer Cells to Doxorubicin by Regulating BMF Expression.  |  Xu, F., et al. 2022. Int J Biol Sci. 18: 1724-1736. PMID: 35280673
6. The Clinical and Cellular Impact of RBMS2 on the Progression and Prognosis of Kidney Renal Clear Cell Carcinoma.  |  Gao, Z. and Fan, S. 2023. Genet Res (Camb). 2023: 5512781. PMID: 38058408
7. Novel susceptibility genes and biomarkers for obstructive sleep apnea: insights from genetic and inflammatory proteins.  |  Zhao, Y., et al. 2025. Sleep. 48: PMID: 39087877
8. LINC01094 promotes gastric cancer through dual targeting of CDKN1A by directly binding RBMS2 and HDAC1.  |  Zhou, X., et al. 2024. Biol Direct. 19: 137. PMID: 39719596
9. SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins.  |  Kanaoka, Y. and Nojima, H. 1994. Nucleic Acids Res. 22: 2687-93. PMID: 8041632
10. Normalization and subtraction: two approaches to facilitate gene discovery.  |  Bonaldo, MF., et al. 1996. Genome Res. 6: 791-806. PMID: 8889548

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RBMS2 Antibody (B-4) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-RBMS2 Antibody (B-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RBMS2 Antibody (B-4) Specifications

Alternate Product Name: RBMS2

Product Clone Name: B-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 271-289

Epitope Target: RBMS2

Epitope Species: human

Product Reactivity/Detection: RBMS2

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for RBMS2 Antibody (B-4): P: Blocking Peptide