Dieser polyklonale Antikörper wird nicht mehr hergestellt. Wir empfehlen Ihnen unseren Rad52 (F-7) monoklonalen Antikörper (Beispielsdaten werden angezeigt).
Rad52 Antikörper (H-300): sc-8350
- Rad52 Antikörper H-300 ist ein polyklonales IgG aus dem Kaninchen in einer Menge von 200 µg/ml
- das Epitop entspricht der Aminosäuresequenz 119-418 lokalisiert am C-terminus von Rad52 aus der Spezies human
- Nicht länger erhältlicher polyklonaler Antikörper
Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. Rad54A of the DEAD-like helicase superfamily binds to double-strand DNA and induces a DNA topological change, which is thought to facilitate homologous DNA pairing, and stimulate DNA recombination. Rad54B of the DEAD-like helicase superfamily binds to double-stranded DNA and displays ATPase activity in the presence of DNA. Rad54B is abundant in testis and spleen, and mutations of this gene occur in primary lymphoma and colon cancer.
Bestellinformation
Rad52 (F-7): sc-365341 [ Empfohlener monoklonaler Ersatz für Rad52 (H-300) ]
| Produkt | Katalog # | EINHEIT | Preis | ANZAHL | Favoriten | |
Rad52 Antikörper (F-7) | sc-365341 | 200 µg/ml | $316.00 | |||
Rad52 (F-7): m-IgG Fc BP-HRP Bundle | sc-527357 | 200 µg Ab; 10 µg BP | $354.00 | |||
Rad52 (F-7): m-IgG1 BP-HRP Bundle | sc-532730 | 200 µg Ab; 20 µg BP | $354.00 | |||
Rad52 Antikörper (F-7) AC | sc-365341 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Rad52 Antikörper (F-7) HRP | sc-365341 HRP | 200 µg/ml | $316.00 | |||
Rad52 Antikörper (F-7) FITC | sc-365341 FITC | 200 µg/ml | $330.00 | |||
Rad52 Antikörper (F-7) PE | sc-365341 PE | 200 µg/ml | $343.00 | |||
Rad52 Antikörper (F-7) Alexa Fluor® 488 | sc-365341 AF488 | 200 µg/ml | $357.00 | |||
Rad52 Antikörper (F-7) Alexa Fluor® 546 | sc-365341 AF546 | 200 µg/ml | $357.00 | |||
Rad52 Antikörper (F-7) Alexa Fluor® 594 | sc-365341 AF594 | 200 µg/ml | $357.00 | |||
Rad52 Antikörper (F-7) Alexa Fluor® 647 | sc-365341 AF647 | 200 µg/ml | $357.00 | |||
Rad52 Antikörper (F-7) Alexa Fluor® 680 | sc-365341 AF680 | 200 µg/ml | $357.00 | |||
Rad52 Antikörper (F-7) Alexa Fluor® 790 | sc-365341 AF790 | 200 µg/ml | $357.00 |