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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
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Labware ships FedEx Ground free of charge to the contiguous US
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Rab 1B Antibody (LD-S3) is a high quality monoclonal Rab 1B antibody (also designated Rab 1B antibody) suitable for the detection of the Rab 1B protein of mouse, rat and human origin. Rab 1B Antibody (LD-S3) is available as the non-conjugated anti-Rab 1B antibody. The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibits 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Can sc-130474: Rab 1B (LD-S3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?
Gefragt von: jerojero
Thank you for your question. Yes, sc-130474: Rab 1B (LD-S3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here:
Rated 1 von
Lucius Chiaraviglio aus
Not a suitable replacement for sc-599Unlike the discontinued sc-599 (rabbit anti-Rab1b), which works great on J774A.1 cells, sc-130474 (mouse anti-Rab1b) doesn't work on J774A.1 cells (only produces very dim diffuse staining). Even tried new secondary antibody to make sure that bad secondary antibody was not the problem.
Rated 4 von
Signal via western blot analysis of Rab 1BSignal via western blot analysis of Rab 1B expression in A-431 whole cell lysate. -SCBT QC
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