Prostaglandin D2 methyl ester CAS: 49852-81-5
MF: C21H34O5
MW: 366.49
A lipid-soluble, cell-permeable PGD2 analog.

Prostaglandin D2 methyl ester (CAS 49852-81-5)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 110ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternative Namen: PGD2 methyl ester
Anwendungen Prostaglandin D2 methyl ester is a lipid-soluble, cell-permeable PGD2 analog
CAS Nummer: 49852-81-5
Molekulargewicht: 366.49
Summenformel: C21H34O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Prostaglandin D2 methyl ester is a more lipid-soluble, cell-permeable prodrug form of prostaglandin D2 (PGD2). Studies have shown that it has a 5-10 fold lower affinity for PGD2 receptors than PGD2.


Literaturhinweise

1. Hayaishi, O., et al., 1988. Sleep-wake regulation by prostaglandins D2 and E2. The Journal of biological chemistry. 263(29): 14593-6. PMID: 3049580
2. Onoe, H., et al., 1988. Prostaglandin D2, a cerebral sleep-inducing substance in monkeys. Proceedings of the National Academy of Sciences of the United States of America. 85(11): 4082-6. PMID: 3163802
3. Giles, H., et al., 1988. The biology and pharmacology of PGD2. Prostaglandins. 35(2): 277-300. PMID: 3283848
4. Suzuki, F., et al., 1987. Methyl ester of prostaglandin D2 as a delivery system of prostaglandin D2 into brain. Biochimica et biophysica acta. 917(2): 224-30. PMID: 3467795
5. Li, Jianjun., et al., 2003. The ethanol metabolite, linolenic acid ethyl ester, stimulates mitogen-activated protein kinase and cyclin signaling in hepatic stellate cells. Life sciences. 73(9): 1083-96. PMID: 12818718
6. Hirai, Hiroyuki., et al., 2003. Gene structure and functional properties of mouse CRTH2, a prostaglandin D2 receptor. Biochemical and biophysical research communications. 307(4): 797-802. PMID: 12878180

Formulierung :
A solution in methyl acetate
Aggregatzustand :
Liquid
LAGERUNG: :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CCCCC[[email protected]@H](/C=C/[[email protected]@H]1[[email protected]]([[email protected]](CC1=O)O)C/C=C\CCCC(=O)OC)O

SDS (MSDS) herunterladen

Analysenzertifikat

Um PDF-Dokumente zu Drucken oder zu Bearbeiten
benötigen Sie Adobe Acrobat Reader

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 111ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 6ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. ist weltweit führend in der Entwicklung von Produkten für den biomedizinischen Forschungsmarkt. Rufen Sie uns an, gebührenfrei unter 00800 4573 8000. .
Copyright © 2007-2021, Santa Cruz Biotechnology, Inc. Alle Rechte vorbehalten. "Santa Cruz Biotechnology", das Santa Cruz Biotechnology, Inc. Logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", das San Juan Ranch Logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz" und "EZ Touch" sind eingetragene Warenzeichen der Santa Cruz Biotechnology, Inc. Alle genannte Warenzeichen sind Eigentum der jeweiligen Inhaber. Alle Rechte vorbehalten.