PBGS Antibody (E-10): sc-398308
- PBGS Antibody (E-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 142-159 within an internal region of PBGS of human origin
- recommended for detection of PBGS of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PBGS Antibody (E-10) for WB applications. These reagents are now offered in bundles with PBGS Antibody (E-10) (see ordering information below).
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SEE ALSO...
PBGS Antibody (E-10) is a mouse monoclonal IgG1 antibody that detects porphobilinogen synthase (PGBS) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-PGBS antibody (E-10) recognizes PGBS, an essential enzyme in the heme biosynthetic pathway, which plays a critical role in the production of heme, cytochromes, and other hemoproteins. PGBS (E-10) monoclonal antibody targets PGBS, which is composed of eight identical subunits, allowing efficient catalysis of the condensation of two molecules of δ-aminolevulinate to form porphobilinogen. This structural arrangement enhances enzyme stability and catalytic efficiency, making PGBS vital for maintaining proper heme levels in the body. Disruptions in PGBS function can lead to serious health issues, including increased sensitivity to lead poisoning and various forms of acute hepatic porphyria, highlighting PGBS importance in both metabolic processes and toxicology. Anti-PGBS antibody (E-10) effectively targets PGBS, making this reagent valuable for researchers studying heme biosynthesis and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PBGS Antibody (E-10) | sc-398308 | 200 µg/ml | $322.00 | |||
PBGS Antibody (E-10): m-IgG Fc BP-HRP Bundle | sc-540929 | 200 µg Ab; 10 µg BP | $361.00 | |||
PBGS Antibody (E-10): m-IgG1 BP-HRP Bundle | sc-542470 | 200 µg Ab; 20 µg BP | $361.00 | |||
PBGS (E-10) Neutralizing Peptide | sc-398308 P | 100 µg/0.5 ml | $69.00 |