Ouabain-d3 (Major)
Alternate Names:
g-Strophanthin-d3
Molecular Weight:
587.67
Molecular Formula:
C29H41D3O12
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Ouabain-d3 (Major) serves as a potent tool in biochemical research, particularly in the study of cellular transport mechanisms. It is a labeled variant of ouabain, distinguished by the incorporation of three deuterium atoms, which makes it invaluable in spectroscopic studies for tracking interactions and dynamics within biological systems. This compound specifically inhibits the Na⁺/K⁺-ATPase pump, a critical enzyme in the regulation of ionic gradients across cellular membranes. By blocking this pump, ouabain-d3 allows researchers to dissect the roles of sodium and potassium ions in cellular processes, including signal transduction, osmoregulation, and the maintenance of cell volume. Its use in research extends to the exploration of the pump′s contributions to intracellular communication networks and its impact on the physiological behavior of cells, thereby providing insights into the fundamental operations that sustain life at the molecular level.
Ouabain-d3 (Major) References
- No endogenous ouabain is detectable in human plasma by ultra-sensitive UPLC-MS/MS. | Baecher, S., et al. 2014. Clin Chim Acta. 431: 87-92. PMID: 24508998
Inhibitor of:
β2-Syntrophin, γ1-Syntrophin, 4933425O20Rik, 6030446N20Rik, AE3, ATAD4, ATP-BL, ATP10A, ATP11A, ATP11B, ATP13A1, ATP13A3, ATP13A5, ATP1AL1, ATP1B3, ATP8A1, ATP8B5, BC048609, C10orf93, C1orf201, C8orf5, calicin, CCDC159, Cdc50B, cyclin M1, DFNB59, Digoxigenin, Dok-2, E030010A14Rik, FAM18B, FXYD7, Gm364, GPR89B, Ik1, IQCE, KIAA1826_8430410K20Rik, LRRC50, MFSD6L, MIP-T3, mKIAA0195, Mmgt2, MP19, MPP4, Na+ CP type Iα, Na+ CP type Iβ, Na+ CP type IIβ, Na+ CP type VIIα, Na+/K+ ATPase β4, Na+/K+-ATPase α3, Na+/K+-ATPase α4, Na+/K+-ATPase β1, Na+/K+-ATPase β2, NCKX2, Neurophysin I, NHEDC2, NKAIN1, NKAIN2, NKAIN3, NKAIN4, Olfr340, OR52E5, OTOP3, PDDC1, PIPES, PQLC2, PQLC3, putrescine ABC transporter permease, SDR-O, SLC10A4, SLC10A5, SLC10A6, SLC10A7, SLC24A1, SLC38A11, SLC38A6, SLC41A1, SLC45A4, SLC46A3, SLC5A12, SMAGP, SNAPC 190, SNAT3, SNAT6, sodium/potassium-ATPase α1, sodium/potassium-ATPase α3, sodium/potassium-ATPase β1, SVOP, taperin, TCP-1 ζ, TMEM101, TMEM107, TMEM14A, TMEM156, TMEM247, TMEM34, TMEM38B, TMEM63B, TMEM87B, TMEM93, TMIE, Vmn2r2, Vmn2r20, Vmn2r31, Vmn2r4, Vmn2r80, and Xg.Activator of:
α-Dystrobrevin, 1100001G20Rik, 1500009C09Rik, 1700006E09Rik, 1700008O03Rik, 1700008P02Rik, 1700009P17Rik, 1700011H22Rik, 1700020A23Rik, 5830482F20Rik, 9130011E15Rik, ABC-me, ABCA16, AI480653, AKAP 149_AKAP 121, Alpha 4, AQP0, AQP12, AQP12B, ATP10C, ATP11C, ATP13A3, ATP13A5, ATP8A2, ATP8B5, BC002199, BC014805, BGT-1, C10orf113, C19orf18, C19orf45, C4orf28, C8A, C8orf73, C9orf172, C9orf69, C9orf91, CaMK1G, CapG, CatSperβ, CCDC112, CCDC114, CCDC128, CCDC164, CCDC28A, CCDC42B, CCDC85A, CCDC92, CdkL4, CLC-3, CLCC1, CLIC5, CT47C1, CXorf38, Cyclosporin A, Dengue Virus 2, DNALI1, ERV3, FAM104B, FAM122C, FAM26A, FAM47C, FAM75A5, FAM90A, FLJ37512, FXYD2, FXYD6, FXYD7, GAGE2A, GAGE7, GATA-5, GCC1, GLB1L3, GlnRS, Gm11127, Gm13718, Gm14195, Gm14325, Gm14431, Gm15455, Gm3336, Gm960, Gm9839, granzyme F, H2-M3, HEATR4, HICE1, HIT-40, HSPC159, Ichthyin, IFLTD1, IQCA, ITBA1, IZUMO4, Kctd12b, KCTD7, KIAA1430_4933411K20Rik, KLHL3, KRTAP9, LHFPL1, Lipocalin-12, LOC145814, LOC147670, LOC197350, LOC285141, LOC375190, LOC388588, LOC389493, LOC401387, LOC440957, LOC498735, LOC644613, LOC646802, LOC689425, LOC728129, LOC729832, LOC732391, LRRC64, Ly-49N, MIC2L1, MIPEP, MiRP1, MS4A10, Na+ CP type IIIα, Na+ CP type IIIβ, Na+ CP type XIα, Na+/K+-ATPase α2, NaS-1, NCCT, NCKX1, NCKX3, NCKX4, NCKX5, nephrocystin-2, Neurensin-2, NHE-4, NHE-9, NKAIN1, NKAIN3, NKCC1, NTT4, Odf2, Olr282, Olr29, Olr307, Olr32, Olr326, Olr34, Olr354, Olr358, Olr361, Olr367, Olr374, Olr382, Olr395, Olr401, Olr404, Olr409, Olr413, Olr418, Olr420, Olr424, Olr437, Olr443, Olr463, Olr482, Olr484, Olr496, Olr507, Olr516, Olr526, Olr532, Olr541, Olr552, Olr556, Olr559, Olr561, Olr575, Olr592, Olr601, Olr608, Olr611, Olr619, Olr634, Olr639, Olr653, Olr657, Olr665, Olr672, Olr690, Olr696, Olr704, Olr709, Olr712, Olr716, Olr724, Olr727, Olr733, Olr736, Olr742, Olr747, Olr749, Olr766, Olr769, Olr773, Olr785, Olr791, Olr80, Olr806, Olr81, Olr831, Olr836, Olr853, Olr879, Olr905, Olr920, Olr951, Olr962, Olr982, OR13C5, OR13D1, OR1B1, OR2AP1, OR8U9, OSR1, OTOP2, OXSR1, PATE-G, PCDHB7, phospholemman, PMCA1, PNPase, Popeye 3, PRELID2, RDS, REEP2, RhBG, RILPL1, SAMD15, SERCA2, SFXN3, Sg V, SLC-1, SLC10A3, SLC10A5, SLC12A8, Slc16a5, Slc22a27, SLC24A1, SLC26A11, SLC35E4, SLC41A2, SLC41A3, SLC43A1, SLC45A4, SLC46A3, SLC4A7, SMR3B, Smuc, SMVT_Slc5a6, sodium/potassium-ATPase α1, sodium/potassium-ATPase α3, sodium/potassium-ATPase β1, SPANX-D, Speedy B, SPEER-3, SPEER-4B, SPEER-4D, SPEER-4F, Telethonin, TMC1, TMC4, TMCO6, TMEM157, TMEM167, TMEM16H, TMEM190, TMEM194B, TMEM22, TMEM225, TMEM229B, TMEM29, TMEM31, TMEM63C, TMEM69, TMEM87A, TPCN2, TRIM41, Troponin T, TTYH1, urotensin IIB, V-ATPase G1, Vmn2r15, Vmn2r8, WDR70, XTP3-B, ZFF29, ZFP11, ZFP110, ZFP119, ZFP184, ZFP213, ZFP26, ZFP316, and ZFP345.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ouabain-d3 (Major), 1 mg | sc-478417 | 1 mg | $516.00 |