Molecular structure of Orotic acid monohydrate, CAS Number: 50887-69-9
Orotic acid monohydrate (CAS 50887-69-9)
Alternate Names:
2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate
CAS Number:
50887-69-9
Purity:
97%
Molecular Weight:
174.11
Molecular Formula:
C5H4N2O4•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Orotic acid monohydrate is a naturally occurring organic compoun. It is classified as a monocarboxylic acid. Orotic acid monohydrate finds wide application in scientific research, where it is used in laboratory experiments. A significant application lies in its role as a precursor to pyrimidine nucleotides, essential for DNA and RNA synthesis. Moreover, Orotic acid monohydrate contributes to the production of orotidine 5′-phosphate, a precursor to uridine 5′-monophosphate, which is vital for nucleic acid synthesis.
Orotic acid monohydrate (CAS 50887-69-9) References
- The synthesis of orotic acid-C14O2H. | LANGLEY, BW. 1954. Yale J Biol Med. 27: 135-8. PMID: 13217401
- Determination of orotic acid, uric acid, and creatinine in milk by liquid chromatography. | Indyk, HE. and Woollard, DC. 2004. J AOAC Int. 87: 116-22. PMID: 15084094
- Orotic acid: a milk constituent Enzymatic determination by means of a new microcalorimetric method. | Anastasi, G., et al. 2000. Talanta. 52: 947-52. PMID: 18968055
- Redetermination of orotic acid monohydrate. | Portalone, G. 2008. Acta Crystallogr Sect E Struct Rep Online. 64: o656. PMID: 21202053
- Orotic acid, a promoter of liver carcinogenesis induces DNA damage in rat liver. | Rao, PM., et al. 1985. Carcinogenesis. 6: 765-8. PMID: 4006060
- Orotic acid sodium salt in kidney stones and urinary deposits. | Christensen, NO., et al. 1983. Scand J Urol Nephrol. 17: 99-104. PMID: 6867631
- Terahertz Spectroscopy and Density Functional Theory Analysis of the Molecular Interactions in Crystalline Orotic Acid Monohydrate | , et al., (2022). Journal of Applied Spectroscopy. volume 89: pages 316–321.
- Hydrogen-bonded neutral and anionic lamellar networks: Crystal structures of bis(O,O′,O″-hydroorotato)disilver(i) dihydrate, potassium hydroorotate and rubidium hydroorotate. Ab initio calculations on orotic acid and the hydroorotate anion† | Somer Bekiroglua and Olof Kristiansson*a. 2002,. J. Chem. Soc., Dalton Trans.,. 1330-1335.
- Matrix isolation infrared spectroscopic and quantum chemical studies on the rotational isomers of orotic acid (6-carboxyuracil) | R Wysokiński, K Helios, L Lapinski, MJ Nowak… - Vibrational …, 2013 - Elsevier. January 2013,. Vibrational Spectroscopy. Volume 64,: Pages 108-118.
- A combined NMR crystallographic and PXRD investigation of the structure-directing role of water molecules in orotic acid and its lithium and magnesium salts† | Ann-Christin Pöppler‡, David Walker ORCID logo and Steven P. Brown. 2017. CrystEngComm,., 19,: 224-236.
- Determination of Orotic Acid by Liquid Chromatography as a Criterion for Calculating Nonfat Milk Solids in Milk Bread Get access Arrow | and Lap V Bui. 1 July 1989,. Journal of Association of Official Analytical Chemists,. Volume 72, Issue 4,: Pages 627–631,.
- Effect of orotic acid as a nucleating agent on the crystallization of bacterial poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) copolymers | and Nicolas Jacquel, Koichirou Tajima, Nobuo Nakamura, Toshio Miyagawa, Pengju Pan, Yoshio Inoue. 15 October 2009. Journal of Applied Polymer Science. Volume114, Issue2: Pages 1287-1294.
- Nucleation mechanism of polyhydroxybutyrate and poly(hydroxybutyrate-co-hydroxyhexanoate) crystallized by orotic acid as a nucleating agent | and Nicolas Jacquel, Koichirou Tajima, Nobuo Nakamura, Hideo Kawachi, Pengju Pan, Yoshio Inoue. 15 January 2010. Journal of Applied Polymer Science. Volume115, Issue2: Pages 709-715.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Orotic acid monohydrate, 25 g | sc-250615 | 25 g | $38.00 | |||
Orotic acid monohydrate, 100 g | sc-250615A | 100 g | $52.00 |