nucleoporin p62 Antibody (D-8): sc-514790
- nucleoporin p62 Antibody (D-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 483-505 at the C-terminus of nucleoporin p62 of rat origin
- recommended for detection of nucleoporin p62 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for nucleoporin p62 Antibody (D-8) for WB applications. These reagents are now offered in bundles with nucleoporin p62 Antibody (D-8) (see ordering information below).
QUICK LINKS
SEE ALSO...
Nucleoporin p62 Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects nucleoporin p62 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Nucleoporin p62 plays a crucial role in the nuclear transport system, acting as a docking protein that facilitates the import and export of various macromolecules, including proteins and nascent mRNA strands, across the nuclear envelope. Anti-nucleoporin p62 antibody (D-8) strategic location at the nuclear pore complex allows interaction with karyopherin proteins, which are essential for recognizing and transporting substrates into the nucleus. Nucleoporin p62′s ability to form homodimers with nuclear transport factor 2 (NTF2) further underscores its importance in maintaining the efficiency and specificity of nuclear transport processes. Anti-nucleoporin p62 antibody (D-8) helps researchers gain valuable insights into the dynamics of nuclear transport and the functional implications of nucleoporin interactions in cellular processes, making this tool indispensable for studies in cell biology and molecular mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
nucleoporin p62 Antibody (D-8) References:
- The gene encoding rat nuclear pore glycoprotein p62 is intronless. | D'Onofrio, M., et al. 1991. J Biol Chem. 266: 11980-5. PMID: 2050692
- Nuclear Pore Protein p62 Autoantibodies in Systemic Lupus Erythematosus. | Kraemer, DM. and Tony, HP. 2010. Open Rheumatol J. 4: 24-7. PMID: 20648220
- TRIB3-P62 interaction, diabetes and autophagy. | Hua, F. and Hu, ZW. 2015. Oncotarget. 6: 34061-2. PMID: 26474463
- p62 works as a hub modulation in the ageing process. | Fan, X., et al. 2022. Ageing Res Rev. 73: 101538. PMID: 34890823
- SQSTM1/P62 promotes lysophagy via formation of liquid-like condensates maintained by HSP27. | Gallagher, ER. and Holzbaur, ELF. 2023. Autophagy. 19: 3029-3030. PMID: 37194327
- The emerging potential role of p62 in cancer treatment by regulating metabolism. | Zhang, X., et al. 2023. Trends Endocrinol Metab. 34: 474-488. PMID: 37349161
- Sequestration of translation initiation factors in p62 condensates. | Danieli, A., et al. 2023. Cell Rep. 42: 113583. PMID: 38096057
- Arginyltransferase 1 modulates p62-driven autophagy via mTORC1/AMPk signaling. | Bonnet, LV., et al. 2024. Cell Commun Signal. 22: 87. PMID: 38297346
- Vaccinia virus subverts xenophagy through phosphorylation and nuclear targeting of p62. | Krause, M., et al. 2024. J Cell Biol. 223: PMID: 38709216
- P62 promotes FSH-induced antral follicle formation by directing degradation of ubiquitinated WT1. | Zhao, T., et al. 2024. Cell Mol Life Sci. 81: 221. PMID: 38763964
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
nucleoporin p62 Antibody (D-8) | sc-514790 | 200 µg/ml | $322.00 | |||
nucleoporin p62 Antibody (D-8): m-IgG Fc BP-HRP Bundle | sc-538700 | 200 µg Ab; 10 µg BP | $361.00 | |||
nucleoporin p62 Antibody (D-8): m-IgGκ BP-HRP Bundle | sc-536362 | 200 µg Ab; 40 µg BP | $361.00 | |||
nucleoporin p62 Antibody (D-8): m-IgG1 BP-HRP Bundle | sc-545841 | 200 µg Ab; 20 µg BP | $361.00 | |||
nucleoporin p62 (D-8) Neutralizing Peptide | sc-514790 P | 100 µg/0.5 ml | $69.00 |