Date published: 2026-8-23

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N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine (CAS 2148-31-4)

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CAS Number:
2148-31-4
Molecular Weight:
258.12
Molecular Formula:
C7H9Cl2NO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine is a metabolite of Trichloroethylene.


N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine (CAS 2148-31-4) References

  1. Specificity of aminoacylase III-mediated deacetylation of mercapturic acids.  |  Newman, D., et al. 2007. Drug Metab Dispos. 35: 43-50. PMID: 17012540
  2. Comparison of Urinary Biomarkers of Exposure in Humans Using Electronic Cigarettes, Combustible Cigarettes, and Smokeless Tobacco.  |  Lorkiewicz, P., et al. 2019. Nicotine Tob Res. 21: 1228-1238. PMID: 29868926
  3. Simultaneous determination of urinary 31 metabolites of VOCs, 8-hydroxy-2'-deoxyguanosine, and trans-3'-hydroxycotinine by UPLC-MS/MS: 13C- and 15N-labeled isotoped internal standards are more effective on reduction of matrix effect.  |  Kuang, H., et al. 2019. Anal Bioanal Chem. 411: 7841-7855. PMID: 31748896
  4. Carcinogen Biomarkers in the Urine of Electronic Cigarette Users and Implications for the Development of Bladder Cancer: A Systematic Review.  |  Bjurlin, MA., et al. 2021. Eur Urol Oncol. 4: 766-783. PMID: 32192941
  5. Exposure to volatile organic compounds may be associated with oxidative DNA damage-mediated childhood asthma.  |  Kuang, H., et al. 2021. Ecotoxicol Environ Saf. 210: 111864. PMID: 33412282
  6. Volatile organic compounds from second-hand smoke may increase susceptibility of children through oxidative stress damage.  |  Kuang, H., et al. 2022. Environ Res. 207: 112227. PMID: 34666018
  7. Co-exposure levels of volatile organic compounds and metals/metalloids in children: Implications for E-waste recycling activity prediction.  |  Kuang, HX., et al. 2023. Sci Total Environ. 863: 160911. PMID: 36528103
  8. Volatile organic compounds and metals/metalloids exposure in children after e-waste control: Implications for priority control pollutants and exposure mitigation measures.  |  Kuang, HX., et al. 2023. J Hazard Mater. 455: 131598. PMID: 37187124
  9. Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage.  |  Werner, M., et al. 1996. Chem Res Toxicol. 9: 41-9. PMID: 8924615
  10. Acute intoxication with trichloroethene: clinical symptoms, toxicokinetics, metabolism, and development of biochemical parameters for renal damage.  |  Brüning, T., et al. 1998. Toxicol Sci. 41: 157-65. PMID: 9520351

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetyl-S-(1,2-dichloroethenyl)-L-cysteine, 10 mg

sc-212092
10 mg
$300.00