mitochondrial ferritin Antibody (6G3): sc-517048

Mitochondrial ferritin Antibody (6G3) is a mouse monoclonal IgG2a kappa light chain antibody that detects mitochondrial ferritin protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-mitochondrial ferritin antibody (6G3) is available as a non-conjugated format. Mitochondrial ferritin plays a crucial role in iron metabolism within mitochondria, where mitochondrial ferritin sequesters excess iron to prevent oxidative damage, thereby maintaining cellular homeostasis. This function is particularly important as dysregulation of iron levels can lead to various pathologies, including neurodegenerative diseases and cancer. Mitochondrial ferritin is primarily located in mitochondria, which are energy-producing organelles of the cell, and proper functioning of mitochondrial ferritin is essential for mitochondrial health and overall cellular function. Additionally, mitochondrial ferritin has been implicated in regulating iron availability for heme synthesis, further underscoring its significance in cellular metabolism. Understanding mitochondrial ferritin and its interactions with other proteins involved in iron metabolism can provide insights into therapeutic strategies for diseases associated with iron dysregulation.

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mitochondrial ferritin Antibody (6G3) References:

1. Duodenal adenomatosis in familial adenomatous polyposis coli. A review of the literature and results from the Heidelberg Polyposis Register.  |  Kadmon, M., et al. 2001. Int J Colorectal Dis. 16: 63-75. PMID: 11355321
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7. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.  |  Du, HY., et al. 2007. Aging Cell. 6: 689-97. PMID: 17875000
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9. A physical map of 15 loci on human chromosome 5q23-q33 by two-color fluorescence in situ hybridization.  |  Saltman, DL., et al. 1993. Genomics. 16: 726-32. PMID: 8325647

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-mitochondrial ferritin Antibody (6G3) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-mitochondrial ferritin Antibody (6G3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

mitochondrial ferritin Antibody (6G3) Specifications

Alternate Product Name: mitochondrial ferritin

Product Clone Name: 6G3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 143-242

Epitope Target: mitochondrial ferritin

Epitope Species: human

Product Reactivity/Detection: mitochondrial ferritin

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for mitochondrial ferritin Antibody (6G3): N/A