Mindin Antibody (A-9): sc-166867

Mindin Antibody (A-9) is a mouse monoclonal IgG2b antibody that detects Mindin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Mindin, also known as Spondin-2 or DIL-1, plays a crucial role in cell adhesion and signaling, particularly in cancer, where differential expression can influence tumor progression and metastasis. This 331 amino acid protein features a unique domain arrangement including an FS1 domain, an FS2 domain, a hydrophobic signal sequence at the N-terminus, and a Thrombospondin type I repeat, which are essential for mediating interactions between cells and the extracellular matrix. Anti-Mindin antibody (A-9) has demonstrated Mindin′s ability to form dimers and oligomers through immunoblot analysis under nonreducing conditions, highlighting Mindin′s importance in cellular communication and potential implications in various pathological conditions. Mindin (A-9) antibody serves as an invaluable tool for researchers investigating Mindin′s roles in development, disease, and therapeutic interventions.

The preferred Mindin antibody is Mindin Antibody (A-10): sc-166868.