LZTFL1 Antibody (1): sc-101533

LZTFL1 Antibody (1) is a mouse monoclonal IgG1 antibody that detects LZTFL1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). LZTFL1, or leucine zipper transcription factor-like protein 1, is a 299 amino acid protein that exhibits a remarkable 90% sequence identity with its murine counterpart, highlighting evolutionary conservation. Anti-LZTFL1 antibody (1) recognizes a protein that plays a crucial role in transcriptional regulation through leucine zipper motif and multiple coiled-coil domains, which facilitate protein-protein interactions essential for gene expression modulation. LZTFL1 is predominantly expressed in various tissues, including liver, brain, lung, and kidney during early development, and in adult tissues such as testis, heart, thymus, pancreas, ovary, prostate, colon, skeletal muscle, and small intestine. The gene encoding LZTFL1 is situated in a tumor suppressor region on chromosome 3, suggesting potential involvement in cancer biology. Two isoforms of LZTFL1, resulting from alternative polyadenylation events, may contribute to functional diversity and regulatory mechanisms. With significant implications in transcriptional control and tumor suppression, LZTFL1 monoclonal antibody (1) serves as a valuable tool for investigating associated molecular pathways.

The preferred LZTFL1 antibody is LZTFL1 Antibody (C-6): sc-376022.