Date published: 2026-4-23

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L-Prolyl-L-isoleucine (CAS 51926-51-3)

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Alternate Names:
H-Pro-Ile-OH
CAS Number:
51926-51-3
Molecular Weight:
228.3
Molecular Formula:
C11H20N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-Prolyl-L-isoleucine is a dipeptide that functions as a substrate in enzymatic reactions. It plays a role in the formation of peptide bonds. This dipeptide interacts with peptidyl transferase, an enzyme found in the ribosome, facilitating the transfer of the growing polypeptide chain from the tRNA in the A site to the tRNA in the P site. L-Prolyl-L-isoleucine′s mechanism of action involves its specific positioning within the ribosome′s catalytic site, allowing for the precise alignment of the amino acids and the formation of the peptide bond.


L-Prolyl-L-isoleucine (CAS 51926-51-3) References

  1. Structure and conformation of peptides involving prolyl residue. IV. L-Prolyl-L-leucine monohydrate.  |  Panneerselvam, K. and Chacko, KK. 1990. Int J Pept Protein Res. 35: 460-4. PMID: 2376471
  2. Towards the Synthesis of a Heterocyclic Analogue of Natural Cyclooligopeptide with Improved Bio-properties.  |  Dahiya, R., et al. 2022. Curr Org Synth. 19: 267-278. PMID: 34636301

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-Prolyl-L-isoleucine, 100 mg

sc-295325
100 mg
$115.00

L-Prolyl-L-isoleucine, 250 mg

sc-295325A
250 mg
$265.00