KLF3 Antibody (KLF3B10F1): sc-81306
- KLF3 Antibody (KLF3B10F1) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to the C-terminal region of KLF3 of human origin
- recommended for detection of KLF3 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for KLF3 Antibody (KLF3B10F1). This work is in progress.
KLF3 Antibody (KLF3B10F1) is a mouse monoclonal IgG1 antibody that detects KLF3 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. KLF3, a member of the Krüppel-like factor family, is a zinc finger-containing transcription factor that plays a crucial role in regulating gene expression during hematopoiesis, the process of blood cell formation. Anti-KLF3 antibody (KLF3B10F1) targets this protein primarily in the nucleus, where KLF3 binds to specific DNA sequences to modulate the transcription of target genes, thereby influencing cell differentiation and proliferation. KLF3′s nuclear localization enables precise control over gene expression in response to various cellular signals, which is vital for maintaining normal hematopoietic function and preventing disorders such as anemia or leukemia. KLF3 monoclonal antibody (KLF3B10F1) serves as an essential tool for researchers studying the regulatory mechanisms of hematopoiesis and the broader implications of KLF family proteins in cellular processes.
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KLF3 Antibody (KLF3B10F1) References:
- KLF3 Mediates Epidermal Differentiation through the Epigenomic Writer CBP. | Jones, J., et al. 2020. iScience. 23: 101320. PMID: 32659720
- KLF3 promotes the 8-cell-like transcriptional state in pluripotent stem cells. | Hao, J., et al. 2020. Cell Prolif. 53: e12914. PMID: 32990380
- miR-130a-Mediated KLF3 Can Inhibit the Growth of Lung Cancer Cells. | Wei, MC., et al. 2021. Cancer Manag Res. 13: 2995-3004. PMID: 33854370
- Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression. | Han, JH., et al. 2022. Autophagy. 18: 518-539. PMID: 34101546
- Silencing of lncRNA KLF3-AS1 represses cell growth in osteosarcoma via miR-338-3p/MEF2C axis. | Chen, C. and Liu, L. 2022. J Clin Lab Anal. 36: e24698. PMID: 36250223
- KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway. | Li, Y., et al. 2023. Lab Invest. 103: 100078. PMID: 36827869
- microRNA-92b-3p augments colon cancer development through inhibiting KLF3. | Liu, X. and Zhang, L. 2023. J Biochem Mol Toxicol. 37: e23488. PMID: 37597242
- Decreased KLF3 Expression via miR-660-5p Targeting Suppresses Gastric Cancer Cell Progression. | Yu, W., et al. 2023. Ann Clin Lab Sci. 53: 771-783. PMID: 37945021
- KLF3 promotes colorectal cancer growth by activating WNT1. | Shen, W., et al. 2024. Aging (Albany NY). 16: 2475-2493. PMID: 38305787
- KLF3 impacts insulin sensitivity and glucose uptake in skeletal muscle. | Fu, S., et al. 2024. Am J Physiol Cell Physiol. 327: C1219-C1235. PMID: 39250818
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KLF3 Antibody (KLF3B10F1) | sc-81306 | 100 µg/ml | $339.00 |