HIP12 Antibody (D-6): sc-390803
- HIP12 Antibody (D-6) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 469-768 mapping within an internal region of HIP12 of human origin
- recommended for detection of HIP12 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for HIP12 Antibody (D-6) for WB applications. This reagent is now offered in a bundle with HIP12 Antibody (D-6) (see ordering information below).
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HIP12 Antibody (D-6) is a mouse monoclonal IgG2a antibody that detects HIP12 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HIP12, a member of the huntingtin interacting protein family, plays a crucial role in the brain, where HIP12 is expressed and exhibits a subcellular distribution pattern similar to that of HIP1, another member of the family. While HIP12 does not directly interact with huntingtin, HIP12 can bind to HIP1, suggesting a potential regulatory role in cellular mechanisms involving huntingtin. HIP12′s importance lies in its non-proapoptotic nature, which may contribute to cellular stability and function in the brain, particularly in the context of neurodegenerative diseases such as Huntington′s disease. Understanding HIP12′s interactions and functions is vital, as these insights may reveal molecular pathways disrupted in Huntington′s disease, highlighting HIP12′s potential as a therapeutic target. anti-HIP12 antibody (D-6) facilitates the study of protein interactions and cellular dynamics, serving as an essential tool for researchers investigating neurodegeneration and huntingtin interacting proteins.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIP12 Antibody (D-6) | sc-390803 | 200 µg/ml | $322.00 | |||
HIP12 Antibody (D-6): m-IgG Fc BP-HRP Bundle | sc-540857 | 200 µg Ab; 10 µg BP | $361.00 |