EGY48 Whole Cell Lysate: sc-364775

EGY48 whole cell lysate is derived from the EGY48 yeast cell line, a specialized strain extensively used in genetic research, particularly for studying gene regulation and protein interactions under controlled experimental conditions. This cell line features a lacZ reporter gene, making it invaluable for assessing the activity of specific transcription factors and the efficacy of their binding to DNA sequences within yeast. The EGY48 lysate allows researchers to investigate the mechanisms of transcriptional activation and repression, providing insights into how certain proteins influence gene expression through interactions with upstream activating sequences (UAS) or silencers. Additionally, it is employed to study the effects of mutations or chemical treatments on the functionality of transcription factors and other regulatory proteins. By enabling detailed analysis of protein-DNA and protein-protein interactions, EGY48 lysate contributes significantly to our understanding of cellular regulation mechanisms in eukaryotic systems. This research is purely scientific, aiming to decipher fundamental biological processes that govern gene expression and regulatory networks, thus advancing knowledge in genetics and molecular biology.