Molecular structure of DPPH, Free Radical, CAS Number: 1898-66-4
DPPH, Free Radical (CAS 1898-66-4)
See product citations (15)
Alternate Names:
1,1-Diphenyl-2-picrylhydrazyl radical; 2,2-Diphenyl-1-picrylhydrazyl (free radical)
Application:
DPPH, Free Radical is a sensitive colormetric free radical scavenger
CAS Number:
1898-66-4
Purity:
≥90%
Molecular Weight:
394.32
Molecular Formula:
C18H12N5O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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DPPH, Free Radical is a cell-permeable, stable free radical that acts as a hydrogen radical scavenger. Originally developed to detect melanin metabolites in the urine of subjects with malignant melanoma, it has found numerous applications as a general antioxidant detector. It is useful in inducing free-radical injury to tissues and as a screening tool for detecting free radical scavenging activity of antioxidants. The ability of a compound to decolorize DPPH free radical signifies the reactivity of the tested compound. DPPH, Free Radical is used in the quantitative determination of aliphatic and aromatic thiols by indirect spectroscopy and for photometric determination of tocopherol.
DPPH, Free Radical (CAS 1898-66-4) References
- 2,2-Diphenyl-1-picrylhydrazyl radical-scavenging active components from Polygonum multiflorum thunb. | Chen, Y., et al. 1999. J Agric Food Chem. 47: 2226-8. PMID: 10794614
- Oxidation of HMG-CoA reductase inhibitors by tert-butoxyl and 1, 1-diphenyl-2-picrylhydrazyl radicals: model reactions for predicting oxidatively sensitive compounds during preformulation. | Karki, SB., et al. 2000. J Pharm Sci. 89: 1518-24. PMID: 11042599
- Synthesis and in vitro studies of pyrone derivatives as scavengers of active oxygen species. | Weber, V., et al. 2001. Arzneimittelforschung. 51: 877-84. PMID: 11765588
- Changes of materials that scavenge 1,1-diphenyl-2-picrylhydrazyl radicals in plasma by per-oral administration of Kampo medicine, Ninjin-yoei-to in rats. | Egashira, T., et al. 2003. J Pharm Pharmacol. 55: 367-71. PMID: 12724043
- Aging of whiskey increases 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity. | Aoshima, H., et al. 2004. J Agric Food Chem. 52: 5240-4. PMID: 15291502
- Determination of DPPH free radical scavenging activity by reversed-phase HPLC: a sensitive screening method for polyherbal formulations. | Chandrasekar, D., et al. 2006. J Pharm Biomed Anal. 40: 460-4. PMID: 16297590
- 2-O-alpha-D-glucopyranosyl-L-ascorbic acid scavenges 1,1-diphenyl-2-picrylhydrazyl radicals via a covalent adduct formation. | Takebayashi, J., et al. 2007. Biosci Biotechnol Biochem. 71: 754-60. PMID: 17341834
- Novel Water Soluble Chitosan Derivatives with 1,2,3-Triazolium and Their Free Radical-Scavenging Activity. | Li, Q., et al. 2018. Mar Drugs. 16: PMID: 29597269
- The Chemistry of DPPH· Free Radical and Congeners. | Ionita, P. 2021. Int J Mol Sci. 22: PMID: 33546504
- Application of High-Performance Liquid Chromatography with Diode Array Detection to Simultaneous Analysis of Reference Antioxidants and 1,1-Diphenyl-2-picrylhydrazyl (DPPH) in Free Radical Scavenging Test. | Tatarczak-Michalewska, M. and Flieger, J. 2022. Int J Environ Res Public Health. 19: PMID: 35886140
- Polyphenol content and antioxidant activity of phytoestrogen containing food and dietary supplements: DPPH free radical scavenging activity by HPLC. | Klarić, DA., et al. 2022. Acta Pharm. 72: 375-388. PMID: 36651542
- An automatic analyzer for the detection of dihydroxyphenylalanine metabolites and other reducing componds in urine. | Banda, PW., et al. 1974. Anal Chem. 46: 1772-7. PMID: 4411963
- Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. | Dinis, TC., et al. 1994. Arch Biochem Biophys. 315: 161-9. PMID: 7979394
- Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical. | Nanjo, F., et al. 1996. Free Radic Biol Med. 21: 895-902. PMID: 8902534
- Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants. | Ancerewicz, J., et al. 1998. Free Radic Biol Med. 25: 113-20. PMID: 9655529
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DPPH, Free Radical, 50 mg | sc-202591 | 50 mg | $60.00 | |||
DPPH, Free Radical, 1 g | sc-202591A | 1 g | $142.00 |