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Molecular structure of Dibenzo[a,e]pyrene, CAS Number: 192-65-4
Dibenzo[a,e]pyrene (CAS 192-65-4)
CAS Number:
192-65-4
Molecular Weight:
302.37
Molecular Formula:
C24H14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Dibenzo[a,e]pyrene is a polyaromatic hydrocarbon with carcinogenic properties. It arises from incomplete combustion of organic material, which can include everything from fossil fuels to biomass. Dibenzo[a,e]pyrene serves as a model compound for understanding the mechanisms of PAH toxicity and mutagenicity. Its interactions with cellular components, particularly DNA, have been a focus of toxicological studies. Research into dibenzo[a,e]pyrene and similar PAHs guides the monitoring of environmental and occupational exposure. The study of dibenzo[a,e]pyrene also contributes to the development of remediation technologies aimed at reducing the impact of PAHs in contaminated sites.
Dibenzo[a,e]pyrene (CAS 192-65-4) References
- Laser-excited time-resolved Shpol'skii spectroscopy for the direct analysis of dibenzopyrene isomers in liquid chromatography fractions. | Yu, S. and Campiglia, AD. 2004. Appl Spectrosc. 58: 1385-93. PMID: 15606949
- Direct determination of dibenzo[a,l]pyrene and its four dibenzopyrene isomers in water samples by solid-liquid extraction and laser-excited time-resolved Shpol'skii spectrometry. | Yu, S. and Campiglia, AD. 2005. Anal Chem. 77: 1440-7. PMID: 15732929
- Identification and determination of highly carcinogenic dibenzopyrene isomers in air particulate samples from a street canyon, a rooftop, and a subway station in Stockholm. | Bergvall, C. and Westerholm, R. 2007. Environ Sci Technol. 41: 731-7. PMID: 17328176
- DNA adducts formation and induction of apoptosis in rat liver epithelial 'stem-like' cells exposed to carcinogenic polycyclic aromatic hydrocarbons. | Topinka, J., et al. 2008. Mutat Res. 638: 122-32. PMID: 17961608
- Metabolism and mutagenicity of dibenzo[a,e]pyrene and the very potent environmental carcinogen dibenzo[a,l]pyrene. | Devanesan, PD., et al. 1990. Chem Res Toxicol. 3: 580-6. PMID: 2103330
- Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene. | ,. 2011. Rep Carcinog. 12: 353-61. PMID: 21863085
- Improved efficiency of extraction of polycyclic aromatic hydrocarbons (PAHs) from the National Institute of Standards and Technology (NIST) Standard Reference Material Diesel Particulate Matter (SRM 2975) using accelerated solvent extraction. | Masala, S., et al. 2011. Anal Bioanal Chem. 401: 3305-15. PMID: 22006242
- Determination of benzo[a]pyrene and dibenzopyrenes in a Chinese coal fly ash certified reference material. | Masala, S., et al. 2012. Sci Total Environ. 432: 97-102. PMID: 22728296
- Covalent binding of dibenzpyrenes and benzo[a]pyrene to DNA: evidence for synergistic and inhibitory interactions when applied in combination to mouse skin. | Hughes, NC. and Phillips, DH. 1990. Carcinogenesis. 11: 1611-9. PMID: 2401051
- Modified ion source triple quadrupole mass spectrometer gas chromatograph for polycyclic aromatic hydrocarbon analyses. | Anderson, KA., et al. 2015. J Chromatogr A. 1419: 89-98. PMID: 26454790
- Determination of high-molecular weight polycyclic aromatic hydrocarbons in high performance liquid chromatography fractions of coal tar standard reference material 1597a via solid-phase nanoextraction and laser-excited time-resolved Shpol'skii spectroscopy. | Wilson, WB., et al. 2016. Talanta. 148: 444-53. PMID: 26653471
- Determination of polycyclic aromatic hydrocarbons in infant formula using solid state urea clathrate formation with gas chromatography - tandem mass spectrometry. | Nyiri, Z., et al. 2017. Talanta. 174: 214-220. PMID: 28738571
- Investigating the importance of edge-structure in the loss of H/H2 of PAH cations: the case of dibenzopyrene isomers. | Castillo, SR., et al. 2018. Int J Mass Spectrom. 429: 189-197. PMID: 30186034
- Emerging PAHs in urban soils: Concentrations, bioaccessibility, and spatial distribution. | Gao, P., et al. 2019. Sci Total Environ. 670: 800-805. PMID: 30921713
- Human cell mutagenicity of oxygenated, nitrated and unsubstituted polycyclic aromatic hydrocarbons associated with urban aerosols. | Durant, JL., et al. 1996. Mutat Res. 371: 123-57. PMID: 9008716
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dibenzo[a,e]pyrene, 100 mg | sc-234557 | 100 mg | $640.00 |