Cytokeratin 5/8 Antibody (5F295): sc-70928
- Cytokeratin 5/8 Antibody (5F295) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against the human lung cancer cell line, MR21
- recommended for detection of Cytokeratin 5/8 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM; may cross-react with Cytokeratin 18
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See pan-Cytokeratin (C11): sc-8018 for Cytokeratin 5/8 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Cytokeratin 5/8 Antibody (5F295) for WB and IHC(P) applications. This reagent is now offered in a bundle with Cytokeratin 5/8 Antibody (5F295) (see ordering information below).
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SEE ALSO...
Cytokeratin 5/8 Antibody (5F295) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 5 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Cytokeratin 5 is a vital component of the cytoskeletal structure in epithelial cells, primarily found in the basal layer of stratified squamous epithelium, where Cytokeratin 5 plays a crucial role in maintaining cellular integrity and resilience against mechanical stress. Cytokeratin 5′s location is significant as anti-Cytokeratin 5 antibody (5F295) contributes to the formation of a robust barrier that protects underlying tissues from injury and infection. Additionally, Cytokeratin 5 is essential for the differentiation of epithelial cells, and Cytokeratin 5 expression is often used as a marker for identifying basal cell carcinomas and other malignancies. Mutations in the gene encoding Cytokeratin 5 (KRT5) can lead to severe skin disorders such as epidermolysis bullosa, highlighting Cytokeratin 5′s importance in both normal physiology and disease states. Anti-Cytokeratin 5 antibody (5F295) is therefore an invaluable tool for researchers studying epithelial biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 5/8 Antibody (5F295) | sc-70928 | 200 µg/ml | $322.00 | |||
Cytokeratin 5/8 Antibody (5F295): m-IgG Fc BP-HRP Bundle | sc-539323 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cytokeratin 5/8 Antibody (5F295) FITC | sc-70928 FITC | 200 µg/ml | $336.00 | |||
Cytokeratin 5/8 Antibody (5F295) PE | sc-70928 PE | 200 µg/ml | $349.00 |