Cdk4 Inhibitor Inhibitor (CAS 546102-60-7)
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Cdk4 Inhibitor is extensively utilized in research focusing on its role in regulating the cell cycle, particularly the transition from the G1 phase to the S phase. This inhibitor targets Cyclin-dependent kinase 4 (Cdk4), a critical enzyme in driving cell cycle progression, making it useful for studying cellular proliferation mechanisms. Research involving Cdk4 Inhibitor often centers on its ability to halt the proliferation of cells, which is essential for understanding the regulation of cell growth and the maintenance of cellular homeostasis. Additionally, Cdk4 Inhibitor is used in studies related to oncology, as the dysregulation of Cdk4 activity is frequently observed in various cancers. Furthermore, this inhibitor helps in exploring the potential roles of Cdk4 in other biological processes such as differentiation and apoptosis, providing broader insights into cellular function and development.
Cdk4 Inhibitor Inhibitor (CAS 546102-60-7) References
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- Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens. | Vymětalová, L. and Kryštof, V. 2015. Med Res Rev. 35: 1156-74. PMID: 26114963
- Longitudinal tracking of single live cancer cells to understand cell cycle effects of the nuclear export inhibitor, selinexor. | Marcus, JM., et al. 2015. Sci Rep. 5: 14391. PMID: 26399741
- The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection. | Edwards, VL., et al. 2019. mBio. 10: PMID: 31409678
- Asymmetric Cell Division of Fibroblasts is An Early Deterministic Step to Generate Elite Cells during Cell Reprogramming. | Song, Y., et al. 2021. Adv Sci (Weinh). 8: 2003516. PMID: 33854891
- Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours. | Schubert, NA., et al. 2022. Eur J Cancer. 170: 196-208. PMID: 35671543
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk4 Inhibitor, 1 mg | sc-203873 | 1 mg | $137.00 |