Cdc34 Antibody (17): sc-135861
- Cdc34 Antibody (17) is a mouse monoclonal IgG2a provided at 50 µg/0.5 ml
- raised against amino acids 108-298 of Cdc34 of human origin
- recommended for detection of Cdc34 of mouse, rat, human and canine origin by WB, IP and IF; not recommended for IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cdc34 Antibody (17). This work is in progress.
Cdc34 Antibody (17) is a mouse monoclonal IgG2a antibody that detects Cdc34 in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Cdc34 plays a crucial role in the cell cycle by acting as a ubiquitin-conjugating enzyme, essential for the transition from G1 phase to S phase of the cell cycle. This transition is vital for proper cell division and replication, ensuring cells are adequately prepared to duplicate DNA before entering mitosis. Anti-Cdc34 antibody (17) recognizes a protein whose activity is closely linked to its structural and functional homolog in yeast, underscoring evolutionary conservation and importance in cellular processes. By facilitating ubiquitination of specific substrates, Cdc34 helps regulate cyclin degradation, thereby controlling cyclin-dependent kinase (Cdk) activity that drives the cell cycle forward. Cdc34′s ability to form stable complexes with proteins like Cdc27 and Cdc16 further highlights an integral role in the anaphase-promoting complex, essential for timely progression of cell division. With broad species reactivity and proven applications, anti-Cdc34 antibody (17) serves as an invaluable tool for researchers studying cell cycle regulation and related pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc34 Antibody (17) | sc-135861 | 50 µg/0.5 ml | $322.00 |