CD1B Antibody (SN13/K5-1B8): sc-65246

CD1B Antibody (SN13/K5-1B8) is a mouse monoclonal IgG1 antibody that detects CD1B in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD1B is a crucial member of the CD1 multigene family, which encodes glycoproteins that play a significant role in the immune response by presenting lipid antigens to T lymphocytes. CD1B is primarily located on the surface of antigen-presenting cells, including dendritic cells and Langerhans cells, where CD1B facilitates the recognition of lipid-based antigens, thereby influencing T cell activation and differentiation. CD1B′s proper functioning is vital for the immune system′s ability to respond to lipid antigens, which are often derived from pathogens. Additionally, CD1B′s interaction with β-2-Microglobulin is essential for stability and surface expression, ensuring effective antigen presentation to T cells. The human CD1 genes, including CD1B, are clustered on chromosome 1q 22-23, highlighting their evolutionary relationship and functional importance in immune regulation. Anti-CD1B antibody (SN13/K5-1B8) is an invaluable tool for researchers studying lipid antigen presentation and T cell responses in human immunology.

The preferred CD1B antibody is CD1B Antibody (O249): sc-19997.