BAF155 Antibody (F-9): sc-365505
- BAF155 Antibody (F-9) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1027-1055 within an internal region of BAF155 of human origin
- recommended for detection of BAF155 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-365505 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BAF155 Antibody (F-9) for WB applications. These reagents are now offered in bundles with BAF155 Antibody (F-9) (see ordering information below).
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BAF155 Antibody (F-9) is a mouse monoclonal IgG2a light chain antibody that detects BAF155 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BAF155, also known as SRG3, is a crucial component of the SWI/SNF chromatin remodeling complex, which plays a vital role in the regulation of gene expression by altering nucleosome structure in an ATP-dependent manner. BAF155 within the SWI/SNF complex is essential for remodeling activity, as BAF155 interacts with other core subunits like Brg-1 and Ini1 to enhance the complex′s ability to facilitate transcriptional activation. This interaction is particularly important because proper functioning of the SWI/SNF complex is linked to various cellular processes, including differentiation and development, and SWI/SNF complex dysregulation has been implicated in several cancers. Anti-BAF155 antibody (F-9) enables researchers to gain insights into chromatin remodeling dynamics and impact on gene regulation, making BAF155 (F-9) antibody an invaluable tool for studies in molecular biology and cancer research.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BAF155 Antibody (F-9) References:
- Monoclonal antibodies reactive with the BAF155 (SMARCC1) and BAF170 (SMARCC2) components of human SWI/SNF-related complexes. | Wang, X., et al. 2005. Hybridoma (Larchmt). 24: 55-7. PMID: 15785210
- Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. | Schaniel, C., et al. 2009. Stem Cells. 27: 2979-91. PMID: 19785031
- Identification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor gene. | DelBove, J., et al. 2011. Epigenetics. 6: 1444-53. PMID: 22139574
- A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. | Harmacek, L., et al. 2014. Dev Neurobiol. 74: 483-97. PMID: 24170322
- CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis. | Wang, L., et al. 2014. Cancer Cell. 25: 21-36. PMID: 24434208
- Structural Insights into BAF47 and BAF155 Complex Formation. | Yan, L., et al. 2017. J Mol Biol. 429: 1650-1660. PMID: 28438634
- Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. | Narayanan, R., et al. 2018. iScience. 4: 109-126. PMID: 30240734
- RBM15 Modulates the Function of Chromatin Remodeling Factor BAF155 Through RNA Methylation in Developing Cortex. | Xie, Y., et al. 2019. Mol Neurobiol. 56: 7305-7320. PMID: 31020615
- A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction. | Han, J., et al. 2020. Int J Mol Sci. 21: PMID: 32244797
- SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site. | Allen, MD., et al. 2021. Commun Biol. 4: 528. PMID: 33953332
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAF155 Antibody (F-9) | sc-365505 | 200 µg/ml | $322.00 | |||
BAF155 Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-537811 | 200 µg Ab; 10 µg BP | $361.00 | |||
BAF155 Antibody (F-9): m-IgGκ BP-HRP Bundle | sc-535213 | 200 µg Ab; 40 µg BP | $361.00 | |||
BAF155 Antibody (F-9): m-IgG2a BP-HRP Bundle | sc-548125 | 200 µg Ab; 10 µg BP | $361.00 | |||
BAF155 (F-9) Neutralizing Peptide | sc-365505 P | 100 µg/0.5 ml | $69.00 | |||
BAF155 Antibody (F-9) X | sc-365505 X | 200 µg/0.1 ml | $322.00 |