Axl Antibody (B-2): sc-166268

Axl Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects Axl in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Axl, a member of the UFO family of receptor tyrosine kinases, plays a crucial role in various cellular processes, including cell survival, proliferation, and migration, making Axl significant in both normal physiology and disease states. Axl is predominantly expressed in heart and skeletal muscle, where Axl is involved in mediating responses to growth factors and regulating immune responses. Notably, Axl has been implicated in the progression of several cancers, including glioblastomas, due to Axl′s ability to promote tumor cell survival and resistance to therapy. The interaction of Axl with ligands, such as Gas6 and Protein S, further underscores Axl′s importance in modulating signaling pathways that influence cell behavior. Anti-Axl antibody (B-2) serves as an essential tool for researchers investigating the roles of receptor tyrosine kinases in health and disease, providing insights into potential therapeutic targets.

The preferred Axl antibody is Axl Antibody (H-3): sc-166269.