ASGPR2/Asialoglycoprotein Receptor 2/ASGR2 Antikörper (3-YD7) ist ein Maus monoklonales IgG2a (kappa light chain) in einer Menge von 100 µg/ml
raised against recombinant ASGPR2 protein of human origin
Empfohlen für die Detektion von ASGPR2 aus der Spezies human per WB, IP und ELISA
Aktuell testen wir noch unsere Sekundärantikörper um das beste Bindeprotein für diesen Primärantikörper ASGPR2/Asialoglycoprotein Receptor 2/ASGR2 (3-YD7) zu finden. Wenn Sie Fragen dazu haben, dann kontaktieren Sie uns bitte.
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health products, bulky and/or heavy items
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The asialoglycoprotein receptor (ASGPR, also designated hepatic lectin) is a type II integral membrane protein and is expressed in hepatic cells. ASGPR is composed of two homologous subunits, ASGPR1 and ASGPR2, that form multimeric complexes. Both ASGPR1 and ASGPR2 contain four functional domains, which include a cytosolic domain, a transmembrane domain, a stalk domain and a carbohydrate recognition domain (CRD). The CRD allows ASGPR to bind glycoproteins with terminal galactose and N-acetylgalactosamine residues while in the presence of calcium. After binding, the ASGPR-glycoprotein complex is then internalized into the cell, where the receptor and ligand are dissociated and ASGPR returns to the cell membrane. ASGPR can also bind hepatitis B virus (HBV) and mediate the HBV-infection of liver cells. The specific interaction with HBV makes ASGPR a potential target for therapeutic purposes.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.