ARL9 Antibody (G-10): sc-393264

ARL9 Antibody (G-10) is a mouse monoclonal IgM antibody that detects ARL9 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ARL9 antibody (G-10) is available as the non-conjugated form. ARL9, also known as ADP-ribosylation factor-like protein 9, is a 187 amino acid protein that plays a crucial role in cellular processes by regulating vesicular trafficking pathways. ARL9 is part of the RAS superfamily of regulatory GTPases and is characterized by a conserved interswitch toggle, which positions ARL9 evolutionarily closer to the Arf family of proteins. Proper functioning of ARL9 is vital for the activation of phospholipase D, an enzyme involved in lipid signaling and membrane dynamics, which are essential for various cellular functions, including secretion and endocytosis. ARL9 gene is located on chromosome 4q12 in humans and 5 C3.3 in mice, highlighting evolutionary conservation across species. Through interactions with other proteins involved in vesicular transport, ARL9 is an important target for studies related to cellular communication and trafficking, making ARL9 (G-10) antibody a valuable tool for researchers investigating these critical biological processes.

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ARL9 Antibody (G-10) References:

1. Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication.  |  Pasqualato, S., et al. 2002. EMBO Rep. 3: 1035-41. PMID: 12429613
2. Isolation of a new member of the ADP-ribosylation like factor gene family, ARL8, from a cartilage cDNA library.  |  Sebald, E., et al. 2003. Gene. 311: 147-51. PMID: 12853149
3. RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors.  |  Louro, R., et al. 2004. Biochem Biophys Res Commun. 316: 618-27. PMID: 15033445
4. Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.  |  Okai, T., et al. 2004. J Cell Sci. 117: 4705-15. PMID: 15331635
5. Arf family GTPases: roles in membrane traffic and microtubule dynamics.  |  Kahn, RA., et al. 2005. Biochem Soc Trans. 33: 1269-72. PMID: 16246095
6. Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins.  |  Kahn, RA., et al. 2006. J Cell Biol. 172: 645-50. PMID: 16505163
7. An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.  |  Hofmann, I. and Munro, S. 2006. J Cell Sci. 119: 1494-503. PMID: 16537643
8. Expression of ADP-ribosylation factor-like protein 8B mRNA in the brain is down-regulated in mice fed a high-fat diet.  |  Haraguchi, T., et al. 2006. Biosci Biotechnol Biochem. 70: 1798-802. PMID: 16861820

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ARL9 Antibody (G-10) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ARL9 Antibody (G-10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ARL9 Antibody (G-10) Specifications

Alternate Product Name: ARL9

Product Clone Name: G-10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 51-78

Epitope Target: ARL9

Epitope Species: mouse

Product Reactivity/Detection: ARL9

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ARL9 Antibody (G-10): P: Blocking Peptide